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Which of the following immune system molecules creates pores in the cell membrane of their target cells to destroy the cell?

  • A. Lymphotoxins
  • B. Perforins
  • C. Interferons
  • D. Cytokines
Correct Answer: B

Rationale: Perforins are immune system molecules that function by creating pores in the cell membrane of target cells. These pores compromise the cell's integrity, ultimately leading to cell destruction. Lymphotoxins induce cell death, but they do not create pores in the cell membrane like perforins. Interferons are signaling proteins that regulate the immune response, while cytokines are a diverse group of proteins involved in cell signaling during immune reactions. Perforins specifically target cell membranes, disrupting their integrity and leading to cell destruction, making them the correct answer in this context.