Nokea
Which of the following is a luminal amebecide drug?
- A. Metronidazole
- B. Emtine
- C. Doxycycline
- D. Dicloxinide
Correct Answer: D
Rationale: Diloxanide (likely misspelled as Dicloxinide) is a luminal amebicide used to eradicate cysts of Entamoeba histolytica in the intestinal lumen, unlike metronidazole, which targets systemic infection.
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A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to:
- A. Ensure the patient will not have increased adverse effects from the tamoxifen
- B. Identify if the patient is a poor metabolizer, potentially reducing conversion to active metabolites
- C. Evaluate risk of drug interactions with tamoxifen
- D. Determine if the patient requires a higher dose due to ultra-rapid metabolism
Correct Answer: B
Rationale: CYP2D6 testing identifies poor metabolizers who may not convert tamoxifen to its active form (endoxifen), impacting efficacy, not just ADRs or interactions .
A nurse has administered drugs to a patient as per the physician's orders. Which of the following activities should the nurse perform after administering the prescribed drugs to the patient?
- A. Record symptoms of the condition.
- B. Perform a culture and sensitivity test.
- C. Obtain history of drug allergy.
- D. Check for adverse drug reactions.
Correct Answer: D
Rationale: After administering the drug to the patient, the nurse should observe the patient for adverse drug reactions. Recording symptoms of infection, performing a culture and sensitivity test, and obtaining a history of drug allergy are typically performed by the nurse in the preadministration assessment stage.
A nurse is teaching a patient about a new prescription for hydrochlorothiazide. Which statement indicates that the patient understands the teaching?
- A. I should increase my potassium intake.
- B. I may experience swelling in my legs.
- C. I need to monitor my blood sugar levels.
- D. I can take this medication any time of the day.
Correct Answer: A
Rationale: Hydrochlorothiazide can cause hypokalemia; increasing potassium intake shows understanding, unlike swelling (opposite effect) or timing flexibility (best in morning).
A competitive antagonist is a substance that:
- A. Interacts receptors and produces submaximal effect
- B. Binds to the same receptor site and progressively inhibits the agonist response
- C. Binds to the nonspecific sites of tissue
- D. Binds to one receptor subtype as an agonist and to another as an antagonist
Correct Answer: B
Rationale: Competitive antagonists compete for the same receptor site, reversibly inhibiting the agonist.
The direct costs of drug therapy include:
- A. The actual cost of acquiring the medication
- B. The loss of income due to illness
- C. Pain and suffering due to inadequate drug therapy
- D. The cost of a funeral associated with premature death
Correct Answer: A
Rationale: Direct costs are the tangible expenses of acquiring the drug itself.