Nokea
Which of the following best describes the effect of propylthiouracil on thyroid hormone production?
- A. It blocks the release of thyrotropin-releasing hormone
- B. It inhibits uptake of iodide by thyroid cells
- C. It prevents the release of thyroid hormone from thyroglobulin
- D. It blocks iodination and coupling of tyrosines in thyroglobulin to form thyroid hormones
Correct Answer: D
Rationale: Propylthiouracil blocks iodination and coupling in thyroglobulin, inhibiting thyroid hormone synthesis.
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Behaviors predictive of addiction to controlled substances include:
- A. Stealing or borrowing another patient's drugs
- B. Requiring increasing doses of opiates for pain associated with malignancy
- C. Receiving refills of a Schedule II prescription on a regular basis
- D. Requesting that only their own primary care provider prescribe for them
Correct Answer: A
Rationale: Stealing/borrowing drugs strongly predicts addiction, unlike cancer-related dose increases or regular refills/provider preference , which may be legitimate.
According to traditional Chinese medicine, if a person who has a fever is given a herb that is yang in nature, such as golden seal, the patient's illness will:
- A. Get worse
- B. Get better
- C. Not be adequately treated
- D. Need additional herbs to treat the yang
Correct Answer: A
Rationale: A yang (warming) herb like golden seal would worsen a fever, a yang condition.
Patients who are being treated with epoetin alfa need to be monitored for the development of:
- A. Thrombocytopenia
- B. Neutropenia
- C. Hypertension
- D. Gout
Correct Answer: C
Rationale: Epoetin alfa can cause hypertension by increasing red cell mass; blood count issues or gout are less common.
A nurse's learning goals for the year include reviewing the most up-to-date information about emergency preparedness related to bioterrorism agents. What should the nurse do?
- A. Read textbooks devoted to the topic
- B. Review best practices around triage and emergency care
- C. Read journal articles about bioterrorism agents
- D. Visit the Centers for Disease Control and Prevention (CDC) Web site
Correct Answer: D
Rationale: The CDC website provides the most current, authoritative bioterrorism preparedness information.
Which drug has a high first pass effect
- A. Amiodarone
- B. Phenytoin
- C. Verapamil
- D. Disopyramide
Correct Answer: C
Rationale: Verapamil undergoes extensive first-pass metabolism in the liver, reducing its bioavailability when taken orally.