Which of the following is characteristic of Gram-negative bacteria?
- A. Thick peptidoglycan layer
- B. Outer membrane containing lipopolysaccharides
- C. Presence of teichoic acids
- D. Absence of a cell wall
Correct Answer: B
Rationale: The correct answer is B: Outer membrane containing lipopolysaccharides. Gram-negative bacteria have an outer membrane that contains lipopolysaccharides, which are important for protection and pathogenicity. This outer membrane is a unique feature of Gram-negative bacteria and is not present in Gram-positive bacteria, making it a key characteristic.
A: Incorrect because Gram-negative bacteria have a thin peptidoglycan layer compared to Gram-positive bacteria.
C: Incorrect because teichoic acids are a characteristic of Gram-positive bacteria, not Gram-negative bacteria.
D: Incorrect because all bacteria, including Gram-negative bacteria, have a cell wall.
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The organism often called “flesh-eating bacteria†is:
- A. Staphylococcus aureus
- B. Staphylococcus epidermidis
- C. Streptococcus pyogenes
- D. Propionibacterium acnes
Correct Answer: C
Rationale: The correct answer is C: Streptococcus pyogenes. This bacterium is commonly known as "flesh-eating bacteria" due to its ability to cause severe tissue destruction and necrotizing fasciitis. Streptococcus pyogenes produces toxins that break down skin and muscle tissues. Staphylococcus aureus (A) can cause skin infections but is not typically associated with necrotizing fasciitis. Staphylococcus epidermidis (B) is a normal skin flora and rarely causes infections. Propionibacterium acnes (D) is associated with acne and not known for causing tissue destruction. Therefore, the correct choice is Streptococcus pyogenes due to its unique ability to cause severe tissue damage and necrotizing fasciitis.
Allergy to penicillin is an example of:
- A. Type I hypersensitivity reaction
- B. Type II hypersensitivity reaction
- C. Type III hypersensitivity reaction
- D. Type IV hypersensitivity reaction
Correct Answer: A
Rationale: Step-by-step rationale for choice A being correct:
1. Penicillin allergy involves IgE antibodies binding to penicillin.
2. This triggers mast cell degranulation, releasing histamine.
3. Histamine causes allergic symptoms like rash, swelling.
4. This immune response characterizes Type I hypersensitivity reactions.
Summary of other choices:
B: Type II reactions involve antibody-mediated cell destruction, not seen in penicillin allergy.
C: Type III reactions involve immune complex deposition, not typical in penicillin allergy.
D: Type IV reactions are delayed hypersensitivity reactions, not immediate like penicillin allergy.
There are several cases of children from boarding school suffering from sore throat. Microscopy of tonsil smears stained according Neisser method has revealed thin yellow bacilli with dark brown grains on their ends placed in the shape of Roman numeral five. What infection can be suspected in this case?
- A. Diphtheria
- B. Scarlet fever
- C. Listeriosis
- D. Tonsilitis
Correct Answer: A
Rationale: Rationale for Correct Answer A (Diphtheria):
1. Thin yellow bacilli with dark brown grains on ends suggest Corynebacterium diphtheriae, characteristic of diphtheria.
2. Roman numeral five shape is typical of diphtheria bacilli.
3. Diphtheria causes sore throat and can spread in boarding schools.
4. Neisser staining method is used for diphtheria bacilli.
Summary of Incorrect Choices:
B: Scarlet fever is caused by Streptococcus pyogenes and presents with rash, not yellow bacilli.
C: Listeriosis is caused by Listeria monocytogenes, not consistent with the described findings.
D: Tonsillitis can be caused by various bacteria or viruses, but the specific characteristics described do not match.
For family Rhabdoviridae is true that:
- A. They are enveloped viruses
- B. They cause plague
- C. They have spherical shape
- D. They infect only humans
Correct Answer: A
Rationale: The correct answer is A: They are enveloped viruses. Rhabdoviridae family consists of enveloped viruses, which means they have a lipid envelope surrounding their protein coat. This envelope helps the virus in infecting host cells and evading the immune system. The other choices are incorrect because B: They cause plague is not true as Rhabdoviridae family typically causes diseases like rabies in mammals. C: They have spherical shape is incorrect as rhabdoviruses have a bullet-shaped structure. D: They infect only humans is also incorrect as Rhabdoviridae viruses can infect a wide range of hosts beyond just humans.
Which strain E. coli can cause bloody diarrhea in children similar to shigellosis
- A. ETEC
- B. EIEC
- C. EAEC
- D. EPEC
Correct Answer: B
Rationale: The correct answer is B: EIEC. This strain of E. coli can cause bloody diarrhea in children similar to shigellosis due to its ability to invade and replicate within the intestinal epithelial cells, leading to inflammation and bloody stools. ETEC (A) causes watery diarrhea due to enterotoxins. EAEC (C) causes persistent diarrhea. EPEC (D) causes attaching and effacing lesions on the intestinal mucosa without invasion.