Nokea
Which one is not true for the adaptive immunity:
- A. Is mainly observed in the skin and mucous membranes
- B. Develops immune memory
- C. Has a specificity
- D. Evolutionary newer in comparison to the innate immunity
Correct Answer: A
Rationale: The correct answer is A because adaptive immunity is not mainly observed in the skin and mucous membranes. Adaptive immunity is a systemic response that involves specific immune cells and antibodies targeting specific pathogens. It develops immune memory (B), meaning it can recognize and respond faster upon re-exposure to the same pathogen. Adaptive immunity also has specificity (C), as it can target specific antigens. Lastly, adaptive immunity is not evolutionarily newer in comparison to innate immunity (D), as both systems have co-evolved to provide comprehensive protection against pathogens.
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A 42-year-old woman has foamy purulent vaginal discharges. Microscopy revealed flagellated protozoa with an undulating membrane and pear-shaped structure. What organism was found?
- A. Trichomonas vaginalis
- B. Trypanosoma gambiense
- C. Leishmania donovani
- D. Lamblia intestinalis
Correct Answer: A
Rationale: The correct answer is A: Trichomonas vaginalis. Trichomonas vaginalis is a sexually transmitted protozoan parasite that causes trichomoniasis, characterized by foamy purulent vaginal discharges. Microscopy of vaginal discharge showing flagellated protozoa with an undulating membrane and pear-shaped structure is indicative of Trichomonas vaginalis. Trypanosoma gambiense causes African sleeping sickness and is transmitted by tsetse flies. Leishmania donovani causes visceral leishmaniasis transmitted by sandflies. Lamblia intestinalis causes giardiasis and is characterized by diarrhea and flatulence.
The complex of non-specific innate defense factors acting against number of infectious agents is known as:
- A. Adaptive immunity
- B. Immune memory
- C. Antibody
- D. Innate immunity (natural resistance)
Correct Answer: D
Rationale: The correct answer is D: Innate immunity (natural resistance). Innate immunity refers to the non-specific defense mechanisms that act against a variety of infectious agents. This includes physical barriers like skin and mucous membranes, as well as cellular components like phagocytes and natural killer cells. Adaptive immunity (A) is specific and involves the production of antibodies and immune memory (B), which are not part of the initial non-specific response. Antibodies (C) are part of the adaptive immune response and are produced in response to specific pathogens, not part of the non-specific innate defense factors.
An 18-year-old patient has developed candidiasis after the case of pneumonia treated with β-lactam antibiotic. What antimycotic agent should be prescribed?
- A. Fluconazole
- B. Streptomycin
- C. Phthalylsulfathiazole
- D. Ampicillin
Correct Answer: A
Rationale: The correct answer is A: Fluconazole.
1. Fluconazole is an antifungal agent effective against Candida species commonly causing candidiasis.
2. Streptomycin (B) is an antibiotic used for bacterial infections, not fungal.
3. Phthalylsulfathiazole (C) is an antibacterial agent, not antifungal.
4. Ampicillin (D) is a β-lactam antibiotic, which can actually contribute to fungal infections like candidiasis.
Which of the following organisms produces aflatoxin, a carcinogenic substance?
- A. Candida albicans
- B. Claviceps purpurea
- C. Aspergillus flavus
- D. Staphylococcus aureus
Correct Answer: C
Rationale: Step-by-step rationale:
1. Aspergillus flavus is a fungus known to produce aflatoxin.
2. Aflatoxin is a potent carcinogen found in contaminated food.
3. Candida albicans is a yeast species not associated with aflatoxin production.
4. Claviceps purpurea is a fungus that produces ergot alkaloids, not aflatoxin.
5. Staphylococcus aureus is a bacterium known for causing food poisoning, not aflatoxin production.
Summary: Aspergillus flavus is the correct answer as it is the organism known to produce aflatoxin, a carcinogenic substance. Other choices are incorrect as they are not associated with aflatoxin production.
Allergy to penicillin is an example of:
- A. Type I hypersensitivity reaction
- B. Type II hypersensitivity reaction
- C. Type III hypersensitivity reaction
- D. Type IV hypersensitivity reaction
Correct Answer: A
Rationale: Step-by-step rationale for choice A being correct:
1. Penicillin allergy involves IgE antibodies binding to penicillin.
2. This triggers mast cell degranulation, releasing histamine.
3. Histamine causes allergic symptoms like rash, swelling.
4. This immune response characterizes Type I hypersensitivity reactions.
Summary of other choices:
B: Type II reactions involve antibody-mediated cell destruction, not seen in penicillin allergy.
C: Type III reactions involve immune complex deposition, not typical in penicillin allergy.
D: Type IV reactions are delayed hypersensitivity reactions, not immediate like penicillin allergy.