Nokea
Which of the following is most descriptive of cAMP?
- A. Second chemical messenger
- B. Catecholamine that contributes to the fight-or-flight response
- C. Steroid
- D. Releasing hormone
Correct Answer: A
Rationale: The correct answer is A: Second chemical messenger. cAMP is a second messenger in cellular signaling pathways, relaying signals from extracellular molecules to intracellular targets. It is not a catecholamine (B), steroid (C), or releasing hormone (D). Catecholamines are a class of neurotransmitters, steroids are lipids with different functions, and releasing hormones are secreted by the hypothalamus to stimulate the release of other hormones. Thus, the most descriptive term for cAMP is a second chemical messenger.
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Hormones produced by the hypothalamus and secreted by the posterior pituitary include:
- A. ADH and aldosterone
- B. ADH and oxytocin
- C. oxytocin and prolactin
- D. cortisol and aldosterone
Correct Answer: B
Rationale: Step 1: The hormones produced by the hypothalamus and secreted by the posterior pituitary are ADH (vasopressin) and oxytocin.
Step 2: ADH regulates water balance by increasing water reabsorption in the kidneys.
Step 3: Oxytocin is involved in uterine contractions during childbirth and milk ejection during breastfeeding.
Step 4: Therefore, choice B (ADH and oxytocin) is correct.
Summary:
- Choice A (ADH and aldosterone) is incorrect because aldosterone is produced by the adrenal glands, not the posterior pituitary.
- Choice C (oxytocin and prolactin) is incorrect because prolactin is produced by the anterior pituitary.
- Choice D (cortisol and aldosterone) is incorrect because cortisol is produced by the adrenal glands, not the posterior pituitary.
Which of the following has both endocrine and exocrine functions?
- A. anterior pituitary
- B. thyroid
- C. adrenal medulla
- D. pancreas
Correct Answer: D
Rationale: The correct answer is D: pancreas. The pancreas has both endocrine (produces hormones like insulin and glucagon) and exocrine (produces digestive enzymes) functions. This dual role makes it unique among the other options. The anterior pituitary (A) is purely endocrine, producing hormones like growth hormone. The thyroid (B) primarily functions as an endocrine gland, producing hormones like thyroxine. The adrenal medulla (C) is also solely endocrine, secreting hormones like epinephrine and norepinephrine. Therefore, the pancreas is the only organ among the choices that performs both endocrine and exocrine functions.
Enlargement of the thyroid gland:
- A. is called a goiter.
- B. causes Addisonian crisis.
- C. makes a person appear cushingoid.
- D. causes hypocalcemic tetany.
Correct Answer: A
Rationale: Step-by-step rationale for why choice A is correct:
1. Enlargement of the thyroid gland is known as a goiter.
2. A goiter can result from various conditions like iodine deficiency or thyroid disorders.
3. It is a common sign of thyroid dysfunction.
4. Goiter may or may not cause symptoms depending on the underlying cause.
5. Therefore, choice A is the correct answer.
Summary:
- Choice B (Addisonian crisis) is incorrect as it is associated with adrenal insufficiency, not thyroid enlargement.
- Choice C (cushingoid appearance) is incorrect as it is related to excess cortisol production, not thyroid enlargement.
- Choice D (hypocalcemic tetany) is incorrect as it is due to low calcium levels, not thyroid enlargement.
Which of the following drugs has muscarinic and nicotinic actions and is resistant to hydrolysis by both true and pseudo cholinesterase:
- A. Acetylcholine
- B. Carbachol
- C. Bethanechol
- D. Succinylcholine
Correct Answer: B
Rationale: Step-by-step rationale for why B (Carbachol) is the correct answer:
1. Carbachol is a cholinergic drug that acts on both muscarinic and nicotinic receptors.
2. It is resistant to hydrolysis by both true and pseudo cholinesterase enzymes.
3. Acetylcholine (A) is rapidly hydrolyzed by both cholinesterases.
4. Bethanechol (C) is a muscarinic agonist but not a nicotinic agonist.
5. Succinylcholine (D) is a depolarizing neuromuscular blocking agent, not a cholinergic agonist.
Summary:
Carbachol is the only drug among the choices that has both muscarinic and nicotinic actions and is resistant to hydrolysis by cholinesterases. Acetylcholine is rapidly hydrolyzed, Bethanechol does not have nicotinic actions, and Succinyl
Which is not Na+ dependent for absorption?
- A. thiamin
- B. riboflavin
- C. niacin
- D. folate
Correct Answer: D
Rationale: The correct answer is D. Folate absorption is not Na+ dependent because it is absorbed in the small intestine through a carrier-mediated process independent of sodium. Thiamin, riboflavin, and niacin require sodium-dependent transport mechanisms for absorption in the small intestine. Thiamin is absorbed through thiamin transporters that are Na+ dependent. Riboflavin is absorbed by sodium-dependent multivitamin transporters. Niacin absorption also involves sodium-dependent transporters. Therefore, folate is the only option that is not Na+ dependent for absorption.