HESI Focus on Maternity Exam Related

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Which of the following is most likely to develop sickle cell anemia?

  • A. European American
  • B. Native American
  • C. African American
  • D. Asian American
Correct Answer: C

Rationale: Sickle cell anemia is most commonly found in individuals of African American descent. This is because sickle cell trait provides some protection against malaria, and historically, regions where malaria is or was prevalent have higher rates of sickle cell anemia. Therefore, individuals with African ancestry are at a higher risk of developing sickle cell anemia compared to other populations. Choices A, B, and D are less likely to develop sickle cell anemia due to lower genetic prevalence in their respective populations.