Which of the following is not a systemic cytokine?
- A. TNF
- B. IL-1
- C. IL-6
- D. IL-8
Correct Answer: D
Rationale: The correct answer is D: IL-8. IL-8 is not a systemic cytokine because it mainly acts locally at the site of inflammation to recruit neutrophils. Systemic cytokines like TNF, IL-1, and IL-6 have widespread effects throughout the body, influencing various immune responses and inflammatory processes. IL-8's localized action distinguishes it from systemic cytokines, making it the correct choice. TNF, IL-1, and IL-6 are all systemic cytokines that play key roles in regulating the immune response and inflammation at a systemic level, unlike IL-8.
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Which of the following statements about M cells is incorrect?
- A. M cells are found in Peyer's patches in the small intestine
- B. M cells are specialized epithelial cells
- C. M' stands for microfold as these cells show small folds on their luminal side rather than microvilli
- D. They specialize in the transport by transcytosis of IgA from the lamina propria (the tissue immediately below the gut lining) into the intestinal lumen
Correct Answer: D
Rationale: The correct answer is D because M cells do not transport IgA from the lamina propria into the intestinal lumen. Instead, they transport antigens and pathogens from the gut lumen to underlying immune cells. Choice A is correct as M cells are found in Peyer's patches. Choice B is correct as M cells are specialized epithelial cells. Choice C is incorrect as M cells have microfolds on their luminal side, not microvilli.
The nurse is assessing a client for signs and symptoms of systemic lupus erythematosus (SLE). Which of the following would be consistent with this disorder? (Select one that does not apply.)
- A. Discoid rash on skin exposed to sunlight
- B. Urinalysis negative for casts and protein
- C. Painful, deformed small joints
- D. Pain on inspiration
Correct Answer: A
Rationale: The correct answer is A: Discoid rash on skin exposed to sunlight. Systemic lupus erythematosus (SLE) commonly presents with a characteristic butterfly-shaped rash on the face, especially over the cheeks and nose, that worsens with sunlight exposure. The rash is not limited to skin exposed to sunlight. Choices B, C, and D are inconsistent with SLE. B: Urinalysis negative for casts and protein is not indicative of SLE, as renal involvement in SLE often presents with the presence of casts and protein in the urine. C: Painful, deformed small joints is more typical of rheumatoid arthritis, not SLE. D: Pain on inspiration is a symptom of pleurisy, which can occur in SLE but is not a defining feature.
Which factors will assist a patient in coping positively with having cancer (select all that apply)?
- A. Feeling of control
- B. Strong support system
- C. Internalization of feelings
- D. Possibility of cure or control
Correct Answer: B
Rationale: Factors such as feeling in control, having a strong support system, and the possibility of cure or control enhance positive coping with cancer.
Which of the following is an important nursing intervention for HIV-positive clients?
- A. Suggesting the use of herbal medications and alternate therapies.
- B. Suggesting the use of psychostimulants such as methamphetamine.
- C. Advising client to avoid clinical drug trials.
- D. Providing referral to support groups and resources for information.
Correct Answer: D
Rationale: Providing referrals to support groups and resources helps clients manage their condition and access necessary care.
You are evaluating an HIV-positive patient who is receiving IV pentamidine (Pentam) as a treatment for Pneumocystis carinii pneumonia. Which information is most important to communicate to the physician?
- A. The blood pressure decreased to 104/76 during administration.
- B. The patient is complaining of pain at the site of the infusion.
- C. The patient is not taking in an adequate amount of oral fluids.
- D. Blood glucose is 55 mg/dL after the medication administration.
Correct Answer: D
Rationale: Pentamidine can cause hypoglycemia which is a serious and potentially life-threatening side effect. A blood glucose level of 55 mg/dL is critically low and requires immediate intervention. The other findings while important are less urgent and can be managed with standard nursing interventions.