Nokea
Which of the following is NOT true. Passive immunization:
- A. Has been used to treat patients newly infected with Ebola
- B. Involves transferring serum from an immune to a non-immune individual
- C. Provides the recipient with protective antibodies
- D. Involves transferring naïve lymphocytes from an immune to a non-immune individual
Correct Answer: D
Rationale: Passive immunization does not involve transferring naïve lymphocytes; instead, it transfers pre-formed antibodies for immediate protection. Choice D is incorrect because lymphocytes do not produce antibodies directly. Choices A, B, and C are correct: Passive immunization has been used for Ebola, transfers serum with antibodies, and provides immediate protection with pre-formed antibodies.
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The rearrangement of gene segments that occurs randomly in B cell receptor genes and T cell receptor genes:
- A. Occurs during clonal expansion of B cells and T cells
- B. Involves rapid genetic mutation after lymphocytes become activated
- C. Allows the mature lymphocyte population to recognize an enormous diversity of antigens
- D. Occurs in the DNA of all cells in the body
Correct Answer: C
Rationale: Step 1: Gene rearrangement in B cell and T cell receptor genes creates unique receptor proteins.
Step 2: This diversity allows mature lymphocytes to recognize a wide range of antigens.
Step 3: This process is crucial for adaptive immune response and antigen specificity.
Step 4: Choices A and B do not accurately describe gene rearrangement.
Step 5: Choice D is incorrect as gene rearrangement is specific to lymphocytes, not all cells in the body.
Which of the following best illustrates selective genetic pressure in immune adaptation?
- A. Rroma populations and their genetic response to Yersinia pestis
- B. Mutation rates in viruses like the flu
- C. Increased pathogen diversity in unvaccinated populations
- D. Non-specific activation of innate immunity
Correct Answer: A
Rationale: Step 1: Selective genetic pressure refers to the process where specific genetic traits are favored due to environmental factors.
Step 2: Rroma populations and their genetic response to Yersinia pestis demonstrate selective genetic pressure as they have developed genetic adaptations to resist the plague bacterium.
Step 3: This adaptation is a result of prolonged exposure to the pathogen, leading to the survival and reproduction of individuals with genetic variations that confer resistance.
Step 4: Other choices are incorrect because mutation rates in viruses like the flu (B) do not necessarily involve genetic pressure, increased pathogen diversity in unvaccinated populations (C) is a consequence of lack of immunity, and non-specific activation of innate immunity (D) is not a selective process based on genetic traits.
Priority Decision: While caring for a patient who is at the nadir of chemotherapy, the nurse establishes the highest priority for nursing actions related to
- A. diarrhea
- B. grieving
- C. risk for infection
- D. inadequate nutritional intake
Correct Answer: C
Rationale: At the nadir, the patient's white blood cell count is lowest, increasing the risk for infection, making it the highest priority.
An essential cofactor for restriction endonuclease enzyme activity is
- A. Zn2+
- B. Mg2+
- C. Co2+
- D. Ca2+
Correct Answer: B
Rationale: The correct answer is B: Mg2+. Mg2+ is an essential cofactor for restriction endonuclease enzymes because it stabilizes the enzyme-substrate complex, promotes proper binding of the enzyme to DNA, and facilitates the catalytic activity of the enzyme. Mg2+ ions help in the coordination of the active site residues and the phosphate backbone of DNA, which is crucial for the cleavage of DNA strands. Zn2+, Co2+, and Ca2+ do not provide the necessary coordination and stabilization required for restriction endonuclease enzyme activity, making them incorrect choices.
A patient was given an IM injection of penicillin in the gluteus maximus and developed dyspnea and weakness within minutes following the injection. Which additional assessment findings indicate that the patient is having an anaphylactoid reaction (select all that apply)?
- A. Wheezing
- B. Hypertension
- C. Rash on arms
- D. Feeling of impending doom
Correct Answer: A
Rationale: Anaphylactoid reactions involve symptoms like wheezing, rash, and a sense of impending doom due to severe allergic response.