Which of the following is the mechanism of action of iodides:
- A. Inhibits organification of iodine
- B. By inhibiting \mathrm{Na}+/ \mathrm{l} - simporter reduce iodine transport in thyroid gland
- C. Inhibits production of trioodthyronine form tetraiodthyronine on periphery
- D. Stimulates peroxidase
Correct Answer: A
Rationale: Iodides inhibit iodine organification, reducing thyroid hormone synthesis in high doses.
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Herbs and supplements are regulated by the U.S. Food and Drug Administration.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Herbs and supplements are not regulated as drugs by the FDA; they fall under dietary supplement rules.
The nurse admits a patient to the unit and learns the patient has recently been diagnosed with chronic renal failure but has not informed the primary care provider of this diagnosis. What is the nurse's first priority?
- A. Administer medications ordered immediately.
- B. Maintain the patient's confidentiality.
- C. Call the admitting physician immediately.
- D. Provide teaching about chronic renal failure
Correct Answer: C
Rationale: Renal failure affects drug clearance; informing the physician ensures safe therapy adjustments.
A patient is prescribed lidocaine for ventricular arrhythmias. Which side effect should the nurse monitor for?
- A. Hypotension
- B. Nausea
- C. Seizures
- D. Bradycardia
Correct Answer: C
Rationale: Lidocaine, a Class IB antiarrhythmic, can cause CNS side effects like seizures at high doses, a key monitoring point.
A patient comes to the ER having his quadriceps muscle constantly contracted, you should give him:
- A. Norepinephrine to stimulate the sympathetic nervous system
- B. An antagonist for Norepinephrine
- C. Agonist for acetylcholine
- D. Both B and C
Correct Answer: D
Rationale: Both B and C are correct: a norepinephrine antagonist (e.g., beta-blocker) or acetylcholine agonist (e.g., to relax via parasympathetic action) could relieve muscle contraction.
Which of the following is not hypoglicemic mechanism of action of metformin?
- A. Enhance insulin release by pancreatic beta cells
- B. Increase cell permeability of glucose and utilisation
- C. Decrease gluconeogenesis
- D. Interfere carbohydrate absorption in the gut
Correct Answer: A
Rationale: Metformin does not enhance insulin release; it improves insulin sensitivity and reduces hepatic glucose production.
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