Which of the following is the primary sign of breast cancer?
- A. A bloody discharge from the nipple
- B. A dimpling of the skin over the lesion
- C. A retraction of the nipple
- D. A painless mass in the breast
Correct Answer: D
Rationale: A painless mass is often the first noticeable sign of breast cancer.
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Which hormone is made by the interstitial cells of the testis?
- A. Estrogen
- B. Testosterone
- C. Human chorionic gonadotropin (hCG)
- D. Luteinizing hormone (LH)
Correct Answer: B
Rationale: Certainly. The correct answer is B: Testosterone. Interstitial cells of the testis, also known as Leydig cells, synthesize and secrete testosterone. Testosterone is the primary male sex hormone responsible for the development of male reproductive tissues and characteristics. Estrogen (A) is primarily produced in the ovaries in females. Human chorionic gonadotropin (hCG) (C) is produced by the placenta during pregnancy. Luteinizing hormone (LH) (D) is secreted by the anterior pituitary gland and stimulates the interstitial cells to produce testosterone.
Regarding lactation
- A. Milk production is controlled by prolactin
- B. The co-exist of estrogen and prolactin is antagonistic
- C. Nipple is lubricated by sebaceous gland
- D. Myoepithelial cell contraction facilitate ejection of milk
Correct Answer: A
Rationale: The correct answer is A because milk production is indeed controlled by prolactin, a hormone secreted by the anterior pituitary gland. Prolactin stimulates the alveoli in the breast to produce milk. Option B is incorrect because estrogen and prolactin actually work synergistically to promote lactation. Option C is incorrect as the nipple is lubricated by Montgomery glands, not sebaceous glands. Option D is incorrect because myoepithelial cell contraction helps in milk ejection, not in milk production.
Which of the following sexually transmitted infections is caused by Treponema pallidum?
- A. Herpes
- B. Venereal warts
- C. Gonorrhea
- D. Syphilis
Correct Answer: D
Rationale: Syphilis is caused by the spirochete bacterium Treponema pallidum.
Spermatogenesis is regulated by a negative feedback control system in which follicle-stimulating hormone (FSH) stimulates the steps in sperm cell formation. What is the negative feedback signal associated with sperm cell production that inhibits pituitary formation of FSH?
- A. Testosterone
- B. Inhibin
- C. Estrogen
- D. Luteinizing hormone
Correct Answer: B
Rationale: The correct answer is B: Inhibin. Inhibin is a hormone secreted by the testes in response to high levels of sperm production. Inhibin acts as a negative feedback signal to the pituitary gland, inhibiting the production of follicle-stimulating hormone (FSH). This helps to regulate spermatogenesis by preventing excessive FSH stimulation.
A: Testosterone is not the negative feedback signal for inhibiting FSH production. While testosterone does play a role in regulating spermatogenesis, it does not directly inhibit pituitary FSH production.
C: Estrogen is not involved in the negative feedback control system of spermatogenesis. Estrogen is more closely associated with the female reproductive system.
D: Luteinizing hormone is not the negative feedback signal for inhibiting FSH production. LH is involved in the regulation of testosterone production, not FSH.
The uterine phase where the thickness of the endometrium doubles is the
- A. Menstrual phase
- B. Preovulatory phase
- C. Proliferative phase
- D. Follicular phase
Correct Answer: C
Rationale: The correct answer is C: Proliferative phase. During this phase, estrogen levels increase, stimulating the endometrium to thicken and proliferate. This prepares the uterus for potential implantation of a fertilized egg. The other choices are incorrect because: A: Menstrual phase is when the endometrium sheds, not thickens. B: Preovulatory phase is characterized by the maturation of the ovarian follicles, not endometrial thickening. D: Follicular phase is synonymous with the preovulatory phase and focuses on ovarian follicle development, not endometrial thickening.