Which of the following mechanisms most accurately describes the blocking action of methimazole?
- A. iodine uptake by the thyroid
- B. organification of iodine in the thyroid
- C. peripheral conversion of T4 to T3
- D. peripheral thyroxine (T4) and T3 receptors
Correct Answer: B
Rationale: Methimazole inhibits thyroperoxidase, blocking iodine organification and thyroid hormone synthesis.
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Janice has elevated LDL, VLDL, and triglyceride levels. Niaspan, an extended-release form of niacin, is chosen to treat her hyperlipidemia. Due to its metabolism and excretion, which of the following laboratory results should be monitored?
- A. Serum alanine aminotransferase
- B. Serum amylase
- C. Serum creatinine
- D. Phenylketonuria
Correct Answer: A
Rationale: Niacin can cause hepatotoxicity, requiring ALT monitoring.
A nurse is teaching a client who has OCD and has a new prescription for Paroxetine. Which of the following instructions should the nurse include?
- A. It can take several weeks before you feel like the medication is helping.
- B. Take the medication just before bedtime to promote sleep.
- C. I should take the medication for a new medical for a excessive urges.
- D. Monitor for weight gain while taking this medication.
Correct Answer: A
Rationale: Paroxetine, an SSRI, takes weeks for full effect , a key point for client expectations.
A nurse is preparing to administer a prescribed drug via an intramuscular injection. Which of the following would be most appropriate for the nurse to do? (Select one that does not apply.)
- A. Always wear gloves.
- B. Cleanse skin at injection site.
- C. Place pressure on the area after removing the needle.
- D. Recap the needle before disposal.
Correct Answer: D
Rationale: When administering an intramuscular injection, the nurse should always wear gloves, cleanse the skin at the injection site prior to administration, aspirate for 5 to 10 seconds after inserting the needle, apply pressure to the area after removing the needle, and never recap the needle.
Kasey fractured his ankle in two places and is asking for medication for his pain. The appropriate first-line medication would be:
- A. Ibuprofen (Advil)
- B. Acetaminophen with hydrocodone (Vicodin)
- C. Oxycodone (Oxycontin)
- D. Oral morphine (Roxanol)
Correct Answer: B
Rationale: Acetaminophen with hydrocodone is suitable for moderate-to-severe fracture pain.
Off-label prescribing is:
- A. Regulated by the U.S. Food and Drug Administration
- B. Illegal by NPs in all states (provinces)
- C. Legal if there is scientific evidence for the use
- D. Regulated by the Drug Enforcement Administration
Correct Answer: C
Rationale: Off-label prescribing is legal with scientific support , not FDA-regulated , universally illegal , or DEA-controlled .