Nokea
Which of the following medications has not hypoglycemic effect:
- A. Insulin
- B. Glucagon
- C. Metformin
- D. Glibenclamid
Correct Answer: B
Rationale: Glucagon raises blood glucose levels, unlike the others which lower it.
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Which of the following NSAIDs has greater inhibitory selectivity for COX-1 than COX-2?
- A. Flurbiprofen
- B. Indomethacin
- C. Diclofenac
- D. Celecoxib
Correct Answer: B
Rationale: Indomethacin is more selective for COX-1, whereas celecoxib is COX-2 selective; others have mixed activity.
Which antiepileptic drug in therapeutic doses causes least sedation?
- A. Primidone
- B. Clonazepam
- C. Phenytoin
- D. Phenobarbitone
Correct Answer: C
Rationale: Phenytoin causes less sedation compared to others.
Which action would the FDA take to expedite drug development and approval for an outbreak of smallpox?
- A. List smallpox as a health orphan disease
- B. Omit the preclinical research phase
- C. Extend the clinical research phase
- D. Fast track the investigational drug
Correct Answer: D
Rationale: Fast tracking prioritizes the drug within the FDA, expediting development for urgent needs like a smallpox outbreak. Orphan disease status, omitting preclinical phases, or extending clinical phases would not align with rapid response needs.
You are the home health nurse caring for a 77-year-old patient with congestive heart failure. When assessing this patient, in relation to their drug therapy, what is one thing that would be important for you to include in your assessment?
- A. Patient's age
- B. Required lifestyle changes
- C. Family members in the community
- D. Compliance with nutritional recommendations
Correct Answer: B
Rationale: Lifestyle changes (e.g., salt restriction) impact CHF drug therapy efficacy and adherence, critical for assessment.
Drugs that are designated Schedule II by the U.S. Drug Enforcement Administration:
- A. Are known teratogens during pregnancy
- B. May not be refilled; a new prescription must be written
- C. Have a low abuse potential
- D. May be dispensed without a prescription unless regulated by the state
Correct Answer: B
Rationale: Schedule II drugs (e.g., opioids) require new prescriptions without refills due to high abuse potential, unlike teratogenicity or OTC status .