Nokea
Which of the following names may be assigned to a drug during the process of development? (Select one that does not apply.)
- A. Chemical name
- B. Official name
- C. Pharmacologic name
- D. Trade name
Correct Answer: C
Rationale: Throughout the process of development, drugs may have several names assigned to them including a chemical name, a generic (nonproprietary) name, an official name, and a trade or brand name.
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Samantha is taking lamotrigine (Lamictal) for her seizures and requests a prescription for combined oral contraceptives (COCs), which interact with lamotrigine and may cause:
- A. Contraceptive failure
- B. Excessive weight gain
- C. Reduced lamotrigine levels, requiring doubling the dose of lamotrigine
- D. Induction of estrogen metabolism, requiring higher estrogen content OCs be prescribed
Correct Answer: C
Rationale: COCs induce lamotrigine metabolism, lowering its levels and requiring dose adjustment.
Patients whose total dose of prednisone will exceed 1 gram will most likely need a second prescription for:
- A. Metformin, a biguanide to prevent diabetes
- B. Omeprazole, a proton pump inhibitor to prevent peptic ulcer disease
- C. Naproxen, an NSAID to treat joint pain
- D. Furosemide, a diuretic to treat fluid retention
Correct Answer: B
Rationale: High-dose prednisone risks ulcers, warranting omeprazole; diabetes or fluid are less immediate.
In post menopausal women who are receiving estrogen replacement therapy, medroxyprogesterone is administered concurrently to reduce the risk of:
- A. Atherosclerosis
- B. Endometrial cancer
- C. Hypertension
- D. Osteoporosis
Correct Answer: B
Rationale: Progestins like medroxyprogesterone reduce estrogen-induced endometrial hyperplasia and cancer risk.
Patient education regarding taking iron replacements includes:
- A. Doubling the dose if they miss a dose to maintain therapeutic levels
- B. Taking the iron with milk or crackers if it upsets their stomach
- C. Iron is best taken on an empty stomach with juice
- D. Antacids such as Tums may help the upset stomach caused by iron therapy
Correct Answer: C
Rationale: Iron absorption is best on an empty stomach with juice; milk or antacids reduce absorption, and doubling risks toxicity.
A nurse is preparing to administer Amoxicillin 20 mg/kg/day PO to divide equally every 12 hr to a preschooler who weighs 44 lb. The amount available is amoxicillin suspension 250 mg/5 mL. how many mL should the nurse administer per dose? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 4
- B. 7
- C. 1
- D. 10
Correct Answer: A
Rationale: Calculation: 44 lb = 20 kg; 20 mg/kg/day 20 kg = 400 mg/day; 400 mg ÷ 2 doses = 200 mg/dose; 200 mg ÷ (250 mg/5 mL) = 4 mL, matching the answer.