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Which of the following proteins are encoded by herpesviruses and required for viral DNA replication?

  • A. viral DNA polymerase
  • B. ribonucleotide reductase
  • C. neuraminidase
  • D. thymidine kinase
Correct Answer: A

Rationale: The correct answer is A: viral DNA polymerase. This enzyme is essential for replicating the viral DNA during the herpesvirus life cycle. It catalyzes the synthesis of new DNA strands using the viral genomic template. Ribonucleotide reductase (B) is involved in nucleotide synthesis, but not directly in DNA replication. Neuraminidase (C) is an enzyme found in influenza viruses, not herpesviruses. Thymidine kinase (D) is an enzyme that phosphorylates thymidine, but its role is more related to nucleotide metabolism rather than viral DNA replication.