Nokea
Which of the following should be included in the nurse's preadministration assessment before administering the first dose of an antineoplastic drug?
- A. Blood glucose
- B. Weight
- C. Fasting lipid panel
- D. Blood pressure
- E. Temperature
Correct Answer: B,D,E
Rationale: The nurse's preadministration assessment before the administration of the first dose of an antineoplastic drug should include the client's vital signs (blood pressure, temperature, pulse, and respiratory rate) and weight (to ensure accurate drug dosing).
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A group of nursing students are reviewing antineoplastic drugs. The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?
- A. Alkylating agents
- B. Plant alkaloids
- C. Antimetabolites
- D. Antineoplastic antibiotics
- E. Retinoids
Correct Answer: B,C
Rationale: Plant alkaloids and antimetabolites are considered cell cycle-specific antineoplastic drugs. Alkylating agents and antineoplastic antibiotics are cell cycle-nonspecific agents. Retinoids are miscellaneous agents.
A nurse should monitor a client closely for increased seizure activity when which of the following antineoplastic drugs are used concomitantly with phenytoin (Dilantin)?
- A. Mercaptopurine (Purinethol)
- B. Busulfan (Busulfex)
- C. Thiotepa (Thioplex)
- D. Doxorubicin (Doxil)
- E. Irinotecan (Camptosar)
Correct Answer: B,C,E
Rationale: Plant alkaloids (irinotecan) and alkylating agents (busulfan and thiotepa) can increase risk of seizure when given with phenytoin (Dilantin).
Which of the following are examples of immediate adverse reactions to an antineoplastic drug that the nurse should discuss with the client prior to drug administration?
- A. Fertility problems
- B. Extravasation
- C. Nausea
- D. Cardiotoxicity
- E. Pulmonary fibrosis
Correct Answer: B,C
Rationale: Nausea, vomiting, and extravasation are examples of immediate reactions to an antineoplastic drug that the nurse should discuss with the client prior to drug administration. Fertility problems, cardiotoxicity, and pulmonary fibrosis are more long-term adverse reactions.
A client visits the health care facility for information on cancer. The client asks the nurse if regular consumption of green tea can cause harm. Which of the following should the nurse inform the client as possible effects of green tea?
- A. Dental caries
- B. Damage to heart
- C. Insomnia
- D. Damage to liver
Correct Answer: C
Rationale: The nurse should inform the client that green tea can cause insomnia because it contains caffeine. Green tea is known to improve dental health and maintain health of the heart and liver.
A client is receiving cisplatin. Based on the nurse's understanding that this drug can be nephrotoxic, the nurse anticipates that the primary health care provider will prescribe which of the following?
- A. Mesna
- B. Leucovorin
- C. Dexrazoxane
- D. Amifostine
Correct Answer: D
Rationale: Amifostine binds with the metabolites of cisplatin to protect the kidneys from the nephrotoxic effects. Mesna would be used with ifosfamide to protect the bladder from hemorrhagic cystitis. Leucovorin is used to provide folic acid to the cells after methotrexate administration. Dexrazoxane is a cardioprotective agent used with doxorubicin.