Nokea
Which of the following statements concerning Influenza Hemagglutinin (HA) and Neuraminidase (N) is incorrect
- A. Both mutate frequently due to antigenic drift
- B. Function of N is to release new viral particles from infected cells
- C. HA binds to terminal sialic acid on cell surface molecules found on lung epithelial cells
- D. Tamiflu interferes with the attachment of HA to sialic acid
Correct Answer: D
Rationale: The correct answer is D. Tamiflu interferes with the function of Neuraminidase (N), not Hemagglutinin (HA). HA binds to sialic acid on cell surface molecules, not N. N's function is to release new viral particles. Both HA and N undergo antigenic drift. Therefore, choice D is incorrect as it misrepresents the mechanism of action of Tamiflu.
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Find the unmatched pair with respect to immune function:
- A. Interferons: protection from viral infections
- B. ROS: killing of engulfed pathogens
- C. Mast cells: acute phase response
- D. Selectins: role in leukocyte extravasation
Correct Answer: C
Rationale: The correct answer is C: Mast cells: acute phase response. Mast cells are actually involved in allergic responses, not the acute phase response of the immune system. The acute phase response is primarily mediated by cytokines and acute-phase proteins. Interferons protect against viral infections, ROS help kill pathogens inside cells, and selectins aid in leukocyte extravasation during inflammation.
The industrial nurse examines an employee who complains of right shoulder pain on abduction. He points with one finger to the exact location of the pain and mentions that he won a racquetball tournament yesterday. The nurse suspects the employee is suffering from which problem?
- A. Rotator cuff tear
- B. Bursitis
- C. Dislocation
- D. Subluxation
Correct Answer: B
Rationale: The correct answer is B: Bursitis. The employee's complaint of shoulder pain on abduction, localized pain with a specific trigger (racquetball tournament), and no mention of trauma or instability suggest an inflammatory condition like bursitis. The other choices are incorrect because a rotator cuff tear typically presents with weakness, dislocation with a history of trauma and visible deformity, and subluxation with recurrent episodes of partial dislocation.
What are the essential nursing actions that should be taken for a client with an immune system disorder?
- A. Monitor client for depression.
- B. Monitor client for infusion reactions.
- C. Review drug references.
- D. Advise the client on modifying the home environment.
Correct Answer: B
Rationale: Monitoring for infusion reactions is critical as clients with immune disorders often receive biologic therapies that can cause severe allergic or infusion-related reactions.
What defect in cellular proliferation is involved in the development of cancer?
- A. A rate of cell proliferation that is more rapid than that of normal body cells
- B. Shortened phases of cell life cycles with occasional skipping of G1 or S phases
- C. Rearrangement of stem cell RNA that causes abnormal cellular protein synthesis
- D. Indiscriminate and continuous proliferation of cells with loss of contact inhibition
Correct Answer: D
Rationale: Cancer involves indiscriminate and continuous proliferation of cells with loss of contact inhibition, which allows cells to grow uncontrollably.
What is characteristic of chronic inflammation?
- A. It may last 2 to 3 weeks.
- B. The injurious agent persists or repeatedly injures tissue.
- C. Infective endocarditis is an example of chronic inflammation.
- D. Neutrophils are the predominant cell type at the site of inflammation.
Correct Answer: B
Rationale: Chronic inflammation occurs when the cause of the initial injury persists or recurs, leading to ongoing tissue damage and repair. Unlike acute inflammation, it involves lymphocytes and macrophages rather than neutrophils.