Nokea
Which of the following statements regarding dietary approaches to obesity treatment is TRUE?
- A. Dietary approaches are not as important as pharmacological approaches
- B. Carbohydrates have a greater satiating effect compared with proteins and fats, especially in individuals with prediabetes and obesity
- C. Intermittent fasting has consistently shown superior weight loss to very-low calorie and ketogenic diets as it is the easiest to adhere to
- D. Patient preference of dietary interventions plays a key part in adherence and ultimately weight loss and maintenance
Correct Answer: D
Rationale: Dietary approaches to obesity vary, but patient preference significantly influences adherence and long-term weight loss success, per behavioral studies making this true. Pharmacological approaches complement, not overshadow, diet. Proteins/fats are more satiating than carbohydrates, especially in prediabetes/obesity. Intermittent fasting's superiority isn't consistent adherence varies, not universally easier than ketogenic or very-low calorie diets. Preference drives sustainability, key for physicians tailoring chronic obesity interventions.
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Which of the following is NOT part of the histology of non-alcoholic steatohepatitis?
- A. Fatty infiltration in liver
- B. Fibrosis of liver
- C. Inflammatory infiltrates in lobules
- D. Cirrhosis
Correct Answer: D
Rationale: NASH histology includes steatosis (fatty infiltration), lobular inflammation, and fibrosis, per pathology definitions. Mallory bodies (intracellular inclusions) are classic but not universal. Cirrhosis is an advanced NAFLD outcome, not a defining NASH feature progression, not initial histology. This distinction aids physicians in staging chronic liver disease accurately.
Endothelial dysfunction is one of the first steps in the development of atherosclerosis. Question: Which factor is NOT involved in endothelial dysfunction?
- A. Haemodynamic changes (e.g. hypertension)
- B. Inflammation
- C. Lipids
- D. Proteinuria
Correct Answer: D
Rationale: Endothelial flops pressure, inflammation, lipids kick it, proteinuria's kidney, not vessel start. Nurses spot this, a chronic dysfunction trio.
What is the cut-off of blood pressure for the diagnosis of hypertension that is recommended by MOH Clinical Practice Guideline?
- A. 120/70 mmHg
- B. 125/75 mmHg
- C. 130/70 mmHg
- D. 140/90 mmHg
Correct Answer: D
Rationale: MOH guidelines hold hypertension at 140/90 mmHg, a conventional cutoff balancing sensitivity and specificity for diagnosis in primary care, aligning with global norms like WHO. Lower thresholds 120/70, 125/75, 130/70, 135/80 catch prehypertension or align with newer AHA standards, but MOH sticks to 140/90 for actionable clarity, triggering treatment to curb stroke or heart risks. This higher bar avoids overdiagnosis in resource-stretched settings, ensuring focus on clear disease, a practical call for managing chronic vascular load.
Tetanus:
- A. is caused by clostridium tetani endotoxin
- B. is associated with a better prognosis if the incubation period is short
- C. can be manifest by rigidity of muscles in close proximity to the area of the initial injury
- D. usually presents with weakness in the extremities which then progresses to the facial muscles
Correct Answer: C
Rationale: Tetanus exotoxin, not endo, long incubation's better, local rigidity fits, not weakness march, autonomic storms. Nurses lock this chronic spasm tale.
Certain drug classes may cause harm in patients with symptomatic (NYHA classes II-IV) reduced ejection Heart failure (HFrEF), and thus should be avoided. If they are strongly indicated, they are to be used with caution, and with close monitoring. Such drugs include all of the following except:
- A. Thiazolidinediones (glitazones, e.g., pioglitazone, rosiglitazone)
- B. Nonsteroidal anti-inflammatory drugs and COX-2 inhibitors
- C. Nutritional supplements (e.g., coenzyme Q10, carnitine, taurine, and antioxidants)
- D. Non-dihydropyridine calcium-channel blockers (verapamil, diltiazem)
Correct Answer: C
Rationale: HFrEF hates fluid and strain glitazones swell, NSAIDs tank kidneys, verapamil/diltiazem slow too much, trastuzumab trashes hearts. Supplements like CoQ10? Neutral or helpful, not harmful, a safe outlier. Clinicians dodge the rest, easing chronic pump woes, not this add-on.