Nokea
Which of the following would likely promote the development of obesity?
- A. a greater proportion of bacteriabetes relative to firmicutes gut microflora
- B. a smaller than normal dopamine response to eating high fat and sugar foods
- C. a smaller than normal increase in ghrelin concentrations prior to eating
- D. a greater than normal increase in hypothalamic neuropeptide Y and agouti-related protein
Correct Answer: D
Rationale: The correct answer is D because an increase in hypothalamic neuropeptide Y and agouti-related protein can lead to increased appetite, reduced energy expenditure, and ultimately promote the development of obesity. Neuropeptide Y stimulates food intake, while agouti-related protein inhibits the regulation of food intake and energy expenditure.
A is incorrect because a greater proportion of bacteriabetes relative to firmicutes gut microflora is not directly linked to the development of obesity. B is incorrect because a smaller dopamine response to high fat and sugar foods would likely lead to reduced intake, not obesity. C is incorrect because a smaller increase in ghrelin concentrations would lead to decreased appetite, which is not conducive to obesity development.
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Stimulation by the parasympathetic nervous system will cause the ______ anal sphincter to ______.
- A. external; relax
- B. external; contract
- C. internal; contract
- D. internal; relax
Correct Answer: D
Rationale: The correct answer is D because the parasympathetic nervous system is responsible for promoting rest and digest functions. The internal anal sphincter is controlled by the autonomic nervous system, specifically the parasympathetic division. When stimulated by the parasympathetic nervous system, the internal anal sphincter will relax, allowing for defecation to occur.
A: The external anal sphincter is under voluntary control, not affected by the parasympathetic nervous system.
B: The external anal sphincter contracts voluntarily, not influenced by the parasympathetic nervous system.
C: The internal anal sphincter contracts under sympathetic stimulation, not parasympathetic.
The Kupffer cells are phagocytic cells found in the _____.
- A. gallbladder
- B. pancreas
- C. intestine
- D. liver
Correct Answer: D
Rationale: The correct answer is D: liver. Kupffer cells are specialized macrophages found in the liver, where they play a crucial role in phagocytosis and immune responses. They help remove debris, toxins, and pathogens from the blood. The other options (A: gallbladder, B: pancreas, C: intestine) are incorrect because Kupffer cells are not typically present in these organs. The liver is the main site for Kupffer cells due to its role in filtering and processing blood.
GIT hormones with a major effect on the stomach include the following except:
- A. Gastrin
- B. Secretin
- C. GIP
- D. Neurotensin
Correct Answer: B
Rationale: Secretin is the correct answer because it is not a hormone that directly affects the stomach. Gastrin stimulates gastric acid secretion, GIP enhances insulin release, and neurotensin regulates gastric motility. Secretin primarily targets the pancreas and liver, stimulating the release of bicarbonate-rich pancreatic juice. This hormone does not have a direct major effect on the stomach like the other options. Therefore, Secretin is the exception among the listed GIT hormones affecting the stomach.
CCK:
- A. increases gastric secretion.
- B. inhibits the stomach motility.
- C. inhibits pancreatic enzyme secretion.
- D. increases pancreatic secretions rich in bicarbonate.
Correct Answer: B
Rationale: Step 1: CCK (Cholecystokinin) is released in response to the presence of fats and proteins in the small intestine.
Step 2: CCK inhibits stomach motility to allow enough time for the gallbladder to release bile.
Step 3: This slowing down of stomach motility aids in the digestion and absorption of fats.
Step 4: Choices A, C, and D are incorrect as CCK does not directly affect gastric secretion, pancreatic enzyme secretion, or increase pancreatic secretions rich in bicarbonate.
What is the role of pepsin in digestion?
- A. Digesting carbohydrates
- B. Digesting fats
- C. Digesting proteins
- D. Digesting nucleic acids
Correct Answer: C
Rationale: The correct answer is C: Digesting proteins. Pepsin is a digestive enzyme produced in the stomach that specifically breaks down proteins into smaller peptides. It works optimally in acidic environments, aiding in the digestion of proteins consumed in the diet. The other choices are incorrect because pepsin does not play a role in digesting carbohydrates (A), fats (B), or nucleic acids (D). Carbohydrates are primarily broken down by enzymes like amylase, fats by lipase, and nucleic acids by nucleases. Thus, pepsin's main function is to digest proteins in the stomach.