Which of these viruses is a laboratory product?
- A. Monkeypox
- B. Variola
- C. Vaccinia
- D. Cowpox
Correct Answer: C
Rationale: Rationale:
1. Vaccinia is a laboratory product used in smallpox vaccination.
2. Variola is the virus that causes smallpox, not a laboratory product.
3. Monkeypox is a naturally occurring virus, not a laboratory product.
4. Cowpox can be found in nature and is used in vaccine production, but it is not a laboratory product like Vaccinia.
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The discipline addressing issues associated with the choice and application of drugs to be used for disease prevention, treatment, and/or diagnosis is:
- A. pharmacotherapeutics
- B. toxicology
- C. pharmacokinetics
- D. pharmacy
Correct Answer: A
Rationale: The correct answer is A: pharmacotherapeutics. Pharmacotherapeutics focuses on the selection and use of drugs for disease prevention, treatment, and diagnosis. It involves determining the most effective and safe medications for specific conditions based on patient factors. Toxicology (B) is the study of the adverse effects of chemicals, including drugs. Pharmacokinetics (C) focuses on drug absorption, distribution, metabolism, and excretion in the body. Pharmacy (D) involves the preparation and dispensing of medications, but does not specifically address drug selection and application for disease management. Therefore, pharmacotherapeutics is the most suitable discipline for addressing the use of drugs in disease management.
Which bacteria are responsible for causing the disease known as syphilis?
- A. Treponema pallidum
- B. Neisseria gonorrhoeae
- C. Chlamydia trachomatis
- D. Escherichia coli
Correct Answer: A
Rationale: The correct answer is A: Treponema pallidum. This bacterium is responsible for causing syphilis due to its unique spiral shape and ability to penetrate intact mucous membranes. It is transmitted through sexual contact or from mother to child during pregnancy. Neisseria gonorrhoeae causes gonorrhea, Chlamydia trachomatis causes chlamydia, and Escherichia coli is a common bacterium found in the gut and not associated with syphilis. Treponema pallidum's specific characteristics and mode of transmission distinguish it from the other choices, making it the correct answer.
Which of the following is a disease caused by a protozoan?
- A. Cat scratch disease
- B. Toxoplasmosis
- C. Relapsing fever
- D. Plague
Correct Answer: B
Rationale: The correct answer is B: Toxoplasmosis. Toxoplasmosis is caused by the protozoan Toxoplasma gondii. The rationale for this is that protozoa are single-celled organisms that can cause diseases in humans. Cat scratch disease (A) is caused by a bacterium, Bartonella henselae. Relapsing fever (C) is caused by the bacterium Borrelia recurrentis. Plague (D) is caused by the bacterium Yersinia pestis. Therefore, the only choice caused by a protozoan is toxoplasmosis, making it the correct answer.
A man died from an acute infectious disease accompanied by fever, jaundice, haemorrhagic rash on the skin and mucous membranes as well as by acute renal insufficiency. Histological examination of renal tissue (stained by Romanovsky-Giemsa method) revealed some convoluted bacteria looking like C and S letters. What bacteria were revealed?
- A. Leptospira
- B. Treponema
- C. Spirilla
- D. Borrelia
Correct Answer: A
Rationale: The correct answer is A: Leptospira. The key features pointing to Leptospira are the presence of convoluted bacteria resembling C and S letters, which is characteristic of Leptospira species. Leptospirosis presents with fever, jaundice, haemorrhagic rash, and acute renal insufficiency. The other choices (B: Treponema, C: Spirilla, D: Borrelia) do not match the histological description or the clinical presentation of the case. Treponema is associated with syphilis, Spirilla with genus Spirochaeta, and Borrelia with Lyme disease, none of which match the given scenario.
Mesophylic bacteria are with temperature optimum:
- A. 25-37 °C
- B. 55-65 °C
- C. 15-18 °C
- D. 38-45 °C
Correct Answer: A
Rationale: The correct answer is A (25-37 °C) because mesophilic bacteria thrive best at moderate temperatures typical of most environments, making 25-37 °C their optimum range. This range allows for optimal enzyme activity and growth. Choice B (55-65 °C) is incorrect as it is more suitable for thermophilic bacteria. Choice C (15-18 °C) is too low for mesophiles to thrive efficiently. Choice D (38-45 °C) is too high and is more suitable for thermophiles. Ultimately, the correct answer aligns with the typical temperature range where mesophilic bacteria are most active and abundant.