Which organelle is responsible for breaking down macromolecules, such as proteins, carbohydrates, and lipids, into their smaller building blocks?
Correct Answer: C
Rationale: Lysosomes are membrane-bound organelles containing digestive enzymes that break down macromolecules, such as proteins, carbohydrates, and lipids, into their smaller building blocks. These enzymes help in the process of intracellular digestion and recycling of cellular components. The Golgi apparatus is involved in processing and packaging proteins for secretion or for use within the cell. Mitochondria are responsible for producing energy in the form of ATP through cellular respiration. The endoplasmic reticulum is involved in protein synthesis and lipid metabolism. Therefore, the correct answer is 'C: Lysosomes' as they specifically function in the breakdown of macromolecules into smaller components, distinguishing them from the other organelles mentioned.