Nokea
Which statement about clonidine is false
- A. Useful in the management of opiate withdrawal syndrome
- B. Claimed to have prophylactic value in migraine
- C. It is alpha-2 receptor stimulant
- D. It is safe on abrupt termination of treatment
Correct Answer: D
Rationale: Abrupt clonidine withdrawal can cause rebound hypertension.
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Which of the following statements best defines how a chemical becomes a drug?
- A. A chemical must have a proven therapeutic value or efficacy without severe toxicity or damaging properties to become a drug.
- B. A chemical becomes a drug when it is introduced into the body to cause a change.
- C. A chemical is considered a drug when the Food and Drug Administration (FDA) approves its release to be marketed.
- D. A chemical must have demonstrated therapeutic value to become a drug.
Correct Answer: A
Rationale: A chemical must undergo a series of tests to determine its therapeutic value and efficacy without severe toxicity or damaging properties before it is termed a drug. Test results are reported to the FDA, which may or may not give approval.
A nurse is caring for an older adult client who has a new prescription for Digoxin and takes multiple other medications. The nurse should recognize that concurrent use of which of the following medications places the client at risk for Digoxin toxicity?
- A. Phenytoin
- B. Verapamil
- C. Warfarin
- D. Aluminum hydroxide
Correct Answer: B
Rationale: Verapamil increases digoxin levels by reducing clearance, risking toxicity.
A nurse is caring for a client who is taking Propylthiouracil. For which of the following adverse effects of this medication should the nurse should be correct
- A. Bradycardia
- B. Insomnia
- C. Heat intolerance
- D. Weight loss
Correct Answer: A
Rationale: Propylthiouracil can cause bradycardia as a rare side effect, requiring monitoring.
Which of the following statements about NSAIDs is true?
- A. Most NSAIDs are weak acids
- B. Most NSAIDs are metabolised by the liver into inactive metabolites
- C. Oxicams tend to have the longest half-lives of all NSAIDs
- D. All of the above
Correct Answer: D
Rationale: All are true: NSAIDs are weak acids, metabolized by the liver, and oxicams (e.g., piroxicam) have long half-lives.
Which of the following is natural mineralcorticoid:
- A. Methylprednisolone
- B. Betamethasone
- C. Triamcinolone
- D. Aldosterone
Correct Answer: D
Rationale: Aldosterone is the natural mineralocorticoid produced by the adrenal glands.