Which statement best describes drug efficacy/toxicity in pediatric patients?
- A. Drug requirements for infants have been extensively studied.
- B. Drug dosage is altered by age and weight in children.
- C. Children always need smaller doses of medication than adults.
- D. Infants and children are not at risk for drug toxicity if the dosage is correct
Correct Answer: B
Rationale: Pediatric dosing adjusts for age and weight due to varying metabolism and body composition.
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A nurse is caring for a client who has a new prescription for Phenelzine for the treatment of depression. Which of the following indicates that the client has developed an adverse effect of this medication?
- A. Orthostatic hypotension
- B. Hearing loss
- C. Gastrointestinal bleeding
- D. Weight loss
Correct Answer: A
Rationale: Phenelzine, an MAOI, commonly causes orthostatic hypotension due to its effect on blood pressure regulation.
The current recommended first line treatment of severe malaria in Kenya is?
- A. Quinine
- B. Fansidar
- C. Artescinate
- D. Artemether - lumefantrine
Correct Answer: C
Rationale: Artesunate (often misspelled as Artescinate) is the recommended first-line treatment for severe malaria in Kenya per WHO and national guidelines, administered IV or IM, followed by oral therapy.
Alpha-beta blockers are especially effective to treat hypertension for which ethnic group?
- A. White
- B. Asian
- C. African American
- D. Native American
Correct Answer: C
Rationale: Alpha-beta blockers are particularly effective in African Americans due to their dual mechanism.
A nurse reviewing a client's health record notes a new prescription for Lisinopril 10 mg PO once every day. The nurse should identify this as which of the following types of prescription?
- A. Single
- B. Stat
- C. Routine
- D. Standing
Correct Answer: C
Rationale: A daily dose (once every day) indicates a routine prescription for ongoing treatment.
Dulcea has type 2 diabetes and a high triglyceride level. She has gemfibrozil prescribed to treat her hypertriglyceridemia. A history of which of the following might contraindicate the use of this drug?
- A. Reactive airway disease/asthma
- B. Inflammatory bowel disease
- C. Allergy to aspirin
- D. Gallbladder disease
Correct Answer: D
Rationale: Gemfibrozil increases gallstone risk, contraindicating its use in gallbladder disease.