Nokea
Which statement by the mother of a child with rheumatic fever (RF) shows she has an understanding of prevention for her other children?
- A. Whenever one of them gets a sore throat, I will give that child an antibiotic.
- B. There is no treatment. It must run its course.
- C. If their culture is positive for group A streptococcus, I will give them their antibiotic.
- D. If their culture is positive for staphylococcus A, I will give them their antibiotic.
Correct Answer: A
Rationale: Preventive antibiotic therapy is indicated when a culture is positive for group A streptococcus, but unnecessary antibiotic use (if the infection is viral) should be avoided.
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The most common cardiac anomaly associated with Coarctation of aorta is
- A. Bicuspid aortic valve
- B. Subaortic ventricular septal defect
- C. Atrial septal defect
- D. Supramitral ring
Correct Answer: A
Rationale: Bicuspid aortic valve is the most common cardiac anomaly associated with coarctation of the aorta.
Klinefelter's syndrome:
- A. Has a karyotype XXV
- B. Is the result of meiotic non-dysjunction
- C. Shows delay in bone age/maturation
- D. Is a recognised cause of hypogonadotrophic hypogonadism
Correct Answer: B
Rationale: Klinefelter's syndrome is caused by meiotic non-dysjunction, resulting in an extra X chromosome (karyotype XXY). It is not inherited as an X-linked recessive trait, and it is not a cause of hypogonadotrophic hypogonadism.
In utero heart failure, often with fetal pleural and pericardial effusions and generalized ascites (nonimmune hydrops fetalis) may occur in
- A. ventricular septal defect
- B. coarctation of aorta
- C. d-Transposition of great arteries
- D. single ventricle
Correct Answer: D
Rationale: Single ventricle anatomy can lead to in utero heart failure and hydrops fetalis.
Which of the following conditions results primarily from mutation in the gene encoding Vitamin D receptor?
- A. Vitamin D dependent rickets type 1
- B. Vitamin D dependent rickets type 2
- C. X-linked hypophosphatemic rickets
- D. Autosomal dominant hypophosphatemic rickets
Correct Answer: B
Rationale: Vitamin D dependent rickets type 2 is caused by mutations in the vitamin D receptor gene, leading to resistance to vitamin D.
Ejection systolic murmur in outflow in a neonate is least likely to be due to
- A. Subaortic membrane
- B. Unicuspid aortic valve
- C. Bicuspid aortic valve
- D. Pulmonary stenosis
Correct Answer: A
Rationale: Subaortic membrane is least likely to cause an ejection systolic murmur in a neonate.