Nokea
Which type of bacteria can survive in extreme salty environments?
- A. Psychrophiles
- B. Halophiles
- C. Thermophiles
- D. Mesophiles
Correct Answer: B
Rationale: The correct answer is B: Halophiles. Halophiles are bacteria that can survive in extreme salty environments. They have adapted to thrive in high salt concentrations. Psychrophiles (A) thrive in cold temperatures, Thermophiles (C) thrive in high temperatures, and Mesophiles (D) thrive in moderate temperatures. Therefore, they are not adapted to survive in extreme salty environments like Halophiles.
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Which bacteria are commonly associated with food poisoning?
- A. Clostridium botulinum and Staphylococcus aureus
- B. Bacillus anthracis and Mycobacterium tuberculosis
- C. Treponema pallidum and Neisseria gonorrhoeae
- D. Escherichia coli and Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Staphylococcus aureus. Clostridium botulinum produces a potent neurotoxin causing botulism, commonly associated with improperly canned foods. Staphylococcus aureus produces toxins causing symptoms of food poisoning. Bacillus anthracis and Mycobacterium tuberculosis are not typically associated with food poisoning. Treponema pallidum and Neisseria gonorrhoeae are bacteria causing sexually transmitted infections. Escherichia coli and Klebsiella pneumoniae are not directly linked to food poisoning.
Enriched growth media:
- A. Belong to the minimal media and inhibit the development of gram+ cocci
- B. Support the development of the target bacteria groups without suppressing the growth of other microorganisms
- C. Are intended for the cultivation of only one microbial species
- D. Support the development of target bacteria groups and suppress the development of other microorganisms
Correct Answer: B
Rationale: The correct answer is B because enriched growth media provide essential nutrients that support the growth of target bacteria groups without inhibiting the growth of other microorganisms. This allows for the selective cultivation of specific microbes while still allowing for the growth of other organisms present in the sample. Choice A is incorrect because enriched media do not belong to minimal media and do not inhibit the development of gram+ cocci. Choice C is incorrect because enriched media can support the growth of multiple microbial species. Choice D is incorrect because enriched media do not suppress the development of other microorganisms but rather provide nutrients to support their growth alongside the target bacteria groups.
Family Parvoviridae can cause all of these, except:
- A. Aplastic crisis in patients with chronic anemia
- B. Herpangina
- C. Fetal infections
- D. Fifth disease
Correct Answer: B
Rationale: The correct answer is B: Herpangina. Family Parvoviridae includes Parvovirus B19, which causes Fifth disease, aplastic crisis in chronic anemia, and fetal infections. Herpangina is caused by Enteroviruses, not Parvoviridae. Parvovirus B19 specifically targets erythroid progenitor cells, leading to anemia in susceptible individuals. Fetal infections can result in hydrops fetalis. Aplastic crisis occurs in patients with chronic anemia due to suppression of erythropoiesis by the virus.
Family Reoviridae does not include:
- A. Orthoreovirus type 3
- B. Orthomyxovirus type 1
- C. Orthoreovirus type 1
- D. Orthoreovirus type 2
Correct Answer: B
Rationale: The correct answer is B: Orthomyxovirus type 1. Family Reoviridae includes Orthoreovirus types 1, 2, and 3. Orthomyxovirus belongs to a different family, Orthomyxoviridae. Therefore, B is the correct answer. Orthoreovirus types 1, 2, and 3 are part of the Reoviridae family. Choice A, C, and D are incorrect because they are all part of the Reoviridae family which includes Orthoreoviruses.
After a prolonged isoniazid treatment, the patient developed polyneuritis, paresthesia, memory disorders, and convulsions. What is the most likely mechanism of the described isoniazid side-effects?
- A. Disruption of cell membrane synthesis
- B. Inhibition of protein synthesis
- C. Inhibition of RNA-synthesis
- D. Inhibition of pyridoxal phosphate synthesis
Correct Answer: D
Rationale: The correct answer is D. Isoniazid inhibits pyridoxal phosphate synthesis, which is the active form of vitamin B6. Pyridoxal phosphate is essential for various enzymatic reactions, including neurotransmitter synthesis and myelin formation. Therefore, isoniazid-induced pyridoxal phosphate deficiency can lead to neurological symptoms like polyneuritis, paresthesia, memory disorders, and convulsions.
A: Disruption of cell membrane synthesis - This is not the mechanism of isoniazid side-effects.
B: Inhibition of protein synthesis - Isoniazid does not directly inhibit protein synthesis.
C: Inhibition of RNA-synthesis - Isoniazid does not inhibit RNA synthesis; it affects vitamin B6 metabolism.