Who is credited with the discovery of phagocytosis?
- A. Edward Jenner
- B. Louis Pasteur
- C. Elie Metchnikoff
- D. Paul Ehrlich
Correct Answer: C
Rationale: The correct answer is C: Elie Metchnikoff. He is credited with the discovery of phagocytosis, the process in which certain cells engulf and digest foreign particles. Metchnikoff's research in the late 19th century laid the foundation for our understanding of the immune system. A: Edward Jenner is known for developing the smallpox vaccine. B: Louis Pasteur is famous for his work on germ theory and pasteurization. D: Paul Ehrlich is known for his contributions to immunology, such as developing the concept of antibodies and chemotherapy.
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The intestinal epithelial cells that specialize in the production of antimicrobial peptides are called:
- A. Goblet cells
- B. Enterocytes
- C. Paneth cells
- D. Epithelial stem cells
Correct Answer: C
Rationale: The correct answer is C: Paneth cells. Paneth cells are specialized intestinal epithelial cells located in the small intestine that produce antimicrobial peptides to help defend against pathogens. They play a crucial role in maintaining gut homeostasis. Goblet cells (A) secrete mucus, enterocytes (B) absorb nutrients, and epithelial stem cells (D) are responsible for cell regeneration, but they do not produce antimicrobial peptides like Paneth cells do.
Which opportunistic disease associated with AIDS is characterized by hyperpigmented lesions of skin, lungs, and gastrointestinal (GI) tract?
- A. Kaposi sarcoma
- B. Candida albicans
- C. Herpes simplex type 1 infection
- D. Varicella-zoster virus infection
Correct Answer: A
Rationale: Kaposi sarcoma is a tumor associated with AIDS and manifests as hyperpigmented lesions on the skin, lungs, and GI tract.
What is the medical term for a deficiency in the production of red blood cells?
- A. Iron deficiency anemia
- B. Sickle cell anemia
- C. Aplastic anemia
- D. Pernicious anemia
Correct Answer: C
Rationale: The correct answer is C: Aplastic anemia. Aplastic anemia is a condition where the bone marrow doesn't produce enough blood cells, including red blood cells. Iron deficiency anemia (A) is caused by a lack of iron in the body, not a deficiency in red blood cell production. Sickle cell anemia (B) is a genetic disorder affecting the shape of red blood cells, not the production. Pernicious anemia (D) is caused by a lack of vitamin B12, which leads to a deficiency in red blood cell production, but it is not the medical term specifically used for this condition.
What is a defining characteristic of immunology as a scientific field?
- A. It is largely static, with few modern discoveries
- B. It is a dynamic field, continually evolving through research
- C. It exclusively studies pathogen biology
- D. It focuses solely on innate immunity
Correct Answer: B
Rationale: The correct answer is B: It is a dynamic field, continually evolving through research. Immunology is constantly evolving due to new discoveries and advancements in technology. Research in immunology leads to a deeper understanding of the immune system and its interactions with pathogens, cancer, and other diseases. This ongoing evolution is essential for the development of new treatments and vaccines.
Explanation of why other choices are incorrect:
A: It is largely static, with few modern discoveries - This is incorrect as immunology is a rapidly advancing field with numerous breakthroughs and discoveries.
C: It exclusively studies pathogen biology - This is incorrect as immunology also encompasses the study of the immune system's responses to various stimuli, not just pathogens.
D: It focuses solely on innate immunity - This is incorrect as immunology covers both innate and adaptive immunity, as well as the interactions between them.
Which type of cancer is most commonly associated with exposure to asbestos?
- A. Lung cancer
- B. Leukemia
- C. Breast cancer
- D. Prostate cancer
Correct Answer: A
Rationale: Asbestos exposure is strongly linked to lung cancer, particularly mesothelioma.