Why is diclofenac combined with misoprostol?
- A. They are synergistic
- B. They are additive
- C. To reduce hepatic side effects
- D. To prevent diclofenac-related gastric ulcers
Correct Answer: D
Rationale: Misoprostol protects against diclofenac-induced gastric ulcers.
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Chlorpropamide metabolism is enhanced by
- A. Ethyl alcohol
- B. Diazepam
- C. Lorazepam
- D. Chloridazepoxide
Correct Answer: A
Rationale: Ethyl alcohol induces hepatic enzymes, enhancing the metabolism of chlorpropamide, a sulfonylurea antidiabetic drug.
All the following induce hepatic enzymes except
- A. Rifampicin
- B. Phenytoin
- C. Barbiturates
- D. Tolbutamide
Correct Answer: D
Rationale: Tolbutamide does not significantly induce enzymes; others do.
An overdose of amitriptyline may precipitate all the following adverse effects EXCEPT:
- A. Cardiac arrhythmias
- B. Hypotension
- C. Sedation
- D. Jaundice
Correct Answer: D
Rationale: Amitriptyline overdose does not typically cause jaundice; it causes anticholinergic and cardiac effects.
Which of the following is a side effect of propylthiouracil?
- A. Agranulocytosis
- B. Arrhythmias
- C. Diabetes
- D. Hypertension
Correct Answer: A
Rationale: Propylthiouracil can cause agranulocytosis, a severe drop in white blood cells.
It is reasonable to recommend supplementation with in the treatment of hyperlipidemia.
- A. Omega-3 fatty acids
- B. Probiotics
- C. Plant sterols
- D. Calcium
Correct Answer: C
Rationale: Plant sterols reduce LDL cholesterol by inhibiting intestinal cholesterol absorption.
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