Nokea
When prescribing an opioid analgesic such as acetaminophen and codeine (Tylenol #3), instructions to the patient should include:
- A. The medication may cause sedation and they should not drive.
- B. Constipation is a common side effect and they should increase fluids and fiber.
- C. Patients should not take any other acetaminophen-containing medications at the same time.
- D. All of the above
Correct Answer: D
Rationale: All are critical: sedation, constipation, and acetaminophen overdose risks.
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Food can alter the pH of the stomach, leading to:
- A. Enhanced drug metabolism
- B. Altered vitamin K absorption
- C. Increased vitamin D absorption
- D. Altered drug bioavailability
Correct Answer: D
Rationale: Changes in stomach pH due to food can affect drug dissolution and absorption, altering bioavailability.
When reviewing the phases of drug development, the nurse finds a discussion about the postmarketing surveillance phase. Which one of the following activities would the nurse expect to find as being carried out during this phase?
- A. Health care providers report adverse effects to FDA.
- B. Healthy volunteers are involved in the test.
- C. In vitro tests are performed using human cells.
- D. The drug is given to patients with the disease.
Correct Answer: A
Rationale: The postmarketing surveillance phase of drug development encourages health care professionals to report adverse effects of drugs to the FDA using MedWatch. Phase 1 of clinical testing involves 20 to 100 healthy volunteers. In vitro testing of the drug on human or animal cells is done in the pre-FDA phase. In Phase 2 of clinical testing, the drug is given to patients with the disease for which the drug is manufactured.
Which of the following can be used with parenteral route for the treatment of diabetes mellitus
- A. Insulin preparations
- B. Sulfonilureas
- C. Biguanides
- D. Acarbose
Correct Answer: A
Rationale: Insulin is the only diabetes medication administered parenterally (e.g., subcutaneous or IV).
The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for the client anticipates that which diagnostic study will be prescribed?
- A. Echocardiography
- B. Electrocardiography
- C. Cervical radiography
- D. Pulmonary function studies
Correct Answer: D
Rationale: Bleomycin is an antineoplastic medication (Chemotherapeutic Agents) that can cause interstitial pneumonitis, which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles, which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity occurs. Options 1, 2, and 3 are unrelated to the specific use of this medication.
BZDs may be used in following situations EXCEPT:
- A. Anaesthesia
- B. Anxiety
- C. Floppy infant syndrome
- D. Epilepsy
Correct Answer: C
Rationale: Benzodiazepines (BZDs) are used in anesthesia, anxiety, and epilepsy, but floppy infant syndrome is a side effect of maternal BZD use, not a condition treated with them.