Nokea
The nurse is caring for a client who has a nasogastric tube in place. The client is to receive an oral medication through the tube. Which action by the nurse would be most appropriate? (Select one that does not apply.)
- A. Not diluting liquids prior to administration
- B. Checking the tube for placement
- C. Dissolving crushed tablets in water prior to administration
- D. Flushing the tube with water after drugs are administered
Correct Answer: A
Rationale: Before administration of an oral drug through an NG tube or gastrostomy tube, the nurse should check the tube for placement, dilute and flush liquid drugs through the tube, crush tablets and dissolve them in water before administering them through the tube, and flush the tube with water after the drugs are placed in the tube to clear the tubing completely.
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Sally has been prescribed aspirin 320 mg per day for her atrial fibrillation. She also takes aspirin four or more times a day for arthritis pain. What are the symptoms of aspirin toxicity for which she would need to be evaluated?
- A. Tinnitus
- B. Diarrhea
- C. Hearing loss
- D. Photosensitivity
Correct Answer: A
Rationale: Tinnitus is an early sign of aspirin toxicity (salicylism); diarrhea or photosensitivity are less specific, and hearing loss is later.
Chlorpropamide metabolism is enhanced by
- A. Ethyl alcohol
- B. Diazepam
- C. Lorazepam
- D. Chloridazepoxide
Correct Answer: A
Rationale: Ethyl alcohol induces hepatic enzymes, enhancing the metabolism of chlorpropamide, a sulfonylurea antidiabetic drug.
An Investigational New Drug is filed with the U.S. Food and Drug Administration:
- A. When the manufacturer has completed phase III trials
- B. When a new drug is discovered
- C. Prior to animal testing of any new drug entity
- D. Prior to human testing of any new drug entity
Correct Answer: D
Rationale: An IND is filed before human testing , after preclinical (animal) studies, to ensure safety before clinical trials begin.
The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for the client anticipates that which diagnostic study will be prescribed?
- A. Echocardiography
- B. Electrocardiography
- C. Cervical radiography
- D. Pulmonary function studies
Correct Answer: D
Rationale: Bleomycin is an antineoplastic medication (Chemotherapeutic Agents) that can cause interstitial pneumonitis, which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles, which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity occurs. Options 1, 2, and 3 are unrelated to the specific use of this medication.
An overdose of amitriptyline may precipitate all the following adverse effects EXCEPT:
- A. Cardiac arrhythmias
- B. Hypotension
- C. Sedation
- D. Jaundice
Correct Answer: D
Rationale: Amitriptyline overdose does not typically cause jaundice; it causes anticholinergic and cardiac effects.