You are meeting with parents of a 10-year-old child who recently develops acute lymphoblastic leukemia (ALL). Which of the following is LEAST likely to increase the risk of CNS relapse in children with ALL?
- A. first traumatic lumbar puncture (LP)
- B. T-cell leukemia
- C. cranial nerve involvement at the time of diagnosis
- D. presence of lymphoblast in the CSF at any time during treatment
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
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Persons with up to 70% prevalence of peculiar facial anatomy are considered risk factors for obstructive sleep apnea EXCEPT
- A. hypotonia
- B. developmental delay
- C. central adiposity
- D. hypothyroidism
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
A parent is receiving discharge teaching following their infant's hypospadias repair. Which instruction should the parent follow?
- A. Apply a warm compress to the infant's surgical site twice daily.
- B. Avoid giving the infant a tub bath for 1 week.
- C. Apply an antibiotic ointment to the infant's penis daily.
- D. Clamp the infant's catheter for 30 minutes every 4 hours.
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Which neurotransmitter mediates the sympathetic response?
- A. Norepinephrine
- B. Prostaglandin
- C. Acetylcholine
- D. Serotonin
Correct Answer: A
Rationale: The sympathetic nervous system is responsible for our "fight or flight" response to stressful situations. Norepinephrine is the primary neurotransmitter that mediates the sympathetic response, acting on adrenergic receptors in various target tissues. It helps to increase heart rate, elevate blood pressure, dilate air passages in the lungs, and mobilize energy stores in the body to prepare for physical exertion or stress. Acetylcholine is another neurotransmitter involved in the sympathetic nervous system, but norepinephrine is the primary mediator of the fight or flight response.
Children with high-risk neuroblastoma have poor survival. Current treatment consists of all the following EXCEPT
- A. surgery
- B. intensive chemotherapy
- C. radiation
- D. allogenic bone marrow transplantation
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
In Acute Leukemia, which of the following is a bad prognostic criterion:
- A. Age more than 2 years
- B. Leukocytosis > 50,000 /cm
- C. No mediastinal mass
- D. No CNS manifestations
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.