Nokea
Zero order kinetics is seen with
- A. Phenytoin
- B. Phenobarbital
- C. Erythromycin
- D. Digoxin
Correct Answer: A
Rationale: Phenytoin exhibits zero-order kinetics at high doses (rate is constant, not proportional).
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The nurse administers a prescribed medication that is supplied as an enteric-coated tablet. The patient asks the nurse about this form of tablet. When describing how this tablet is absorbed, which response by the nurse would be most accurate?
- A. The medication dissolves directly from the stomach into the body.'
- B. The drug breaks up into pieces as it moves through the stomach.'
- C. The medication bypasses the GI tract and goes quickly into the bloodstream.'
- D. The drug dissolves into fragments after it reaches your small intestine.'
Correct Answer: D
Rationale: Enteric-coated tablets disintegrate or fragment after reaching the alkaline medium of the small intestine. Tablets and capsules break up into small particles and dissolve into body fluids in the gastrointestinal tract. Liquids and parenteral drugs are quickly absorbed into the body system.
A nurse is assisting with caring for a client with cancer who is receiving cisplatin. Select the adverse effects that the nurse monitors for that are associated with this medication. (Select one that does not apply.)
- A. Tinnitus
- B. Ototoxicity
- C. Hyperkalemia
- D. Hypomagnesemia
Correct Answer: C
Rationale: Cisplatin is an alkylating medication. Alkylating medications are cell cycle phase-nonspecific medications that affect the synthesis of DNA by causing the cross-linking of DNA to inhibit cell reproduction. Cisplatin may cause ototoxicity, tinnitus, hypokalemia, hypocalcemia, hypomagnesemia, and nephrotoxicity. Amifostine (Ethyol) may be administered before cisplatin to reduce the potential for renal toxicity. Correct answers include: 1 (Tinnitus), 2 (Ototoxicity), 5 (Nephrotoxicity), 6 (Hypomagnesemia).
A primary health care provider orders a transdermal drug. When administering this drug, which action by the nurse would be most appropriate?
- A. Apply next dose to a new site.
- B. Check the infusion rate.
- C. Inject only the inner part of the forearm.
- D. Give small volumes of doses.
Correct Answer: A
Rationale: An important nursing intervention when administrating drugs through the transdermal route is to apply the next dose to a new site. It is important to check the infusion rate every 15 to 30 minutes in patients using infusion controllers or infusion pumps. When using the intradermal route, the inner part of the forearm should be used as the injection site and small volumes of doses should be administered.
Medication agreements or 'Pain Medication Contracts' are recommended to be used:
- A. Universally for all prescribing for chronic pain
- B. For patients who have repeated requests for pain medication
- C. When you suspect a patient is exhibiting drug-seeking behavior
- D. For patients with pain associated with malignancy
Correct Answer: A
Rationale: Pain contracts are recommended universally for chronic pain to set expectations, not just for repeated requests , suspicion , or cancer .
Which of the following statement is not correct for insulin medications:
- A. Effective for treatment of diabetes type I
- B. Effective for treament of diabetes type II
- C. Is for parenteral use
- D. Is for intravenous use only
Correct Answer: D
Rationale: Insulin is not exclusively for IV use; it's typically subcutaneous, though IV is used in emergencies.