During what phase of the nursing process would the nurse be required to consider the efficacy of nursing interventions related to drug therapy?
- A. Assessment
- B. Nursing diagnosis
- C. Interventions
- D. Evaluation
Correct Answer: D
Rationale: Evaluation phase assesses the effectiveness of interventions, including those related to drug therapy.
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A client is taking Humulin NPH insulin daily every morning. The nurse reinforces instructions for the client and tells the client that the most likely time for a hypoglycemic reaction to occur is:
- A. 2 to 4 hours after administration
- B. 4 to 12 hours after administration
- C. 16 to 18 hours after administration
- D. 18 to 24 hours after administration
Correct Answer: B
Rationale: Humulin NPH is an intermediate-acting insulin. The onset of action is 1.5 hours, it peaks in 4 to 12 hours, and its duration of action is 24 hours. Hypoglycemic reactions most likely occur during peak time.
Idiosyncrasy is:
- A. A genetically determined abnormal reaction to drugs
- B. A characteristic toxic effect at therapeutic doses
- C. An altered physiological state produced by repeated drug use
- D. An immunologically mediated reaction
Correct Answer: A
Rationale: Idiosyncrasy is a genetically determined unusual response to a drug, e.g., G6PD deficiency with primaquine.
Vera, age 70, has isolated systolic hypertension. Calcium channel blocker dosages for her should be:
- A. Started at about half the usual dosage
- B. Not increased over the usual dosage for an adult
- C. Given once daily because of memory issues in the older adult
- D. Withheld if she experiences gastroesophageal reflux
Correct Answer: A
Rationale: Elderly patients start at half dose due to reduced metabolism and clearance.
Drug which interferes with metabolism of theophylline is:
- A. Erythromycin
- B. Gentamicin
- C. Penicillin
- D. Furazolidone
Correct Answer: A
Rationale: Erythromycin inhibits P-450, increasing theophylline levels.
Attenuated vaccines are also known as:
- A. Killed vaccines
- B. Booster vaccines
- C. Inactivated vaccines
- D. Live vaccines
Correct Answer: D
Rationale: Attenuated vaccines are live, weakened forms, unlike killed/inactivated or booster-specific vaccines.