A nurse is caring for a client who is receiving moderate sedation with Diazepam IV. The client is oversedated. Which of the following medications should the nurse anticipate administering to this client?
- A. Ketamine
- B. Naltrexone
- C. Flumazenil
- D. Fluvoxamine
Correct Answer: C
Rationale: Flumazenil reverses benzodiazepine oversedation, like diazepam.
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A patient who has chronic liver disease reports contact with a person who has tuberculosis (TB). The nurse will counsel this patient to contact the provider to discuss
- A. a chest x-ray
- B. a TB skin test
- C. liver function tests (LFTs)
- D. prophylactic antitubercular drugs
Correct Answer: B
Rationale: TB exposure requires a skin test first; chest x-ray follows if positive, and LFTs or prophylaxis aren't initial steps. Patients who have exposure to TB should have a TB skin test.
A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):
- A. Cytotoxic hypersensitivity reaction
- B. Immune complex hypersensitivity
- C. Immediate hypersensitivity reaction
- D. Delayed hypersensitivity reaction
Correct Answer: A
Rationale: Neutropenia from Silvadene (silver sulfadiazine) is a Type II cytotoxic reaction , targeting blood cells, not immune complex , immediate , or delayed .
Select a suitable therapeutic indication for bethanechol:
- A. To decrease the heart rate
- B. To decrease the blood pressure
- C. For urinary retention
- D. Decrease intraocular pressure
Correct Answer: C
Rationale: Bethanechol, a muscarinic agonist, stimulates bladder contraction for urinary retention.
The volume of distribution (Vd) for a drug that is completely retained in the vascular compartment would be?
- A. High
- B. Low
- C. Unchanged
- D. Cannot be determined
Correct Answer: B
Rationale: A drug confined to the vascular compartment (e.g., plasma) has a low Vd, close to plasma volume (about 0.06 L/kg), indicating limited distribution.
Drug which interferes with metabolism of theophylline is:
- A. Erythromycin
- B. Gentamicin
- C. Penicillin
- D. Furazolidone
Correct Answer: A
Rationale: Erythromycin inhibits P-450, increasing theophylline levels.