Nokea
Amphetamine should not be taken with.....
- A. Paracetamol
- B. Aspirin
- C. MAO inhibitors
- D. Benzimidazole
Correct Answer: C
Rationale: Amphetamines combined with MAO inhibitors can cause a hypertensive crisis due to excessive catecholamine accumulation, a well-known dangerous interaction.
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Which cephalosporin generation is effective against methicillin-resistant Staphylococcus aureus (MRSA)?
- A. First generation
- B. Second generation
- C. Third generation
- D. Fifth generation
Correct Answer: D
Rationale: Fifth-generation cephalosporins, like ceftaroline, are effective against MRSA, unlike earlier generations.
Therapeutic index of a drug is an indicator of
- A. Potency
- B. Safety
- C. Toxicity
- D. Efficacy
Correct Answer: C
Rationale: Therapeutic index (TD50/ED50) measures the margin between therapeutic and toxic doses.
Drugs do not metabolize the same way in all people. For what patient would a nurse expect to assess for an alteration in drug metabolism?
- A. A 35-year-old woman with cervical cancer
- B. A 41-year-old man with kidney stones
- C. A 50-year-old man with cirrhosis of the liver
- D. A 62-year-old woman in acute renal failure
Correct Answer: C
Rationale: The liver is the most important site of drug metabolism. If the liver is not functioning effectively, as in patients with cirrhosis, drugs will not metabolize normally so that toxic levels could develop unless dosage is reduced. A patient with cervical cancer or kidney stones would not be expected to have altered ability to metabolize drugs so long as no liver damage existed. The patient with renal failure would have altered excretion of the drugs through the renal system but metabolism would not be impacted.
The first step in the prescribing process according to the World Health Organization is:
- A. Choosing the treatment
- B. Educating the patient about the medication
- C. Diagnosing the patient's problem
- D. Starting the treatment
Correct Answer: C
Rationale: The WHO prescribing process begins with diagnosing the problem to ensure treatment aligns with the condition, followed by choosing therapy and education.
Oral iron supplements are prescribed for a 6 year-old child with iron deficiency anemia. The nurse instructs the mother to administer the iron with which best food item?
- A. Milk
- B. Water
- C. Apple juice
- D. Orange juice
Correct Answer: D
Rationale: Vitamin C increases the absorption of iron by the body. The mother should be instructed to administer the medication with a citrus fruit or a juice that is high in vitamin C. Milk may affect absorption of the iron. Water will not assist in absorption. Orange juice contains a greater amount of vitamin C than apple juice.