The following drug causes a decrease in aqueous humour secretions from the ciliary body:
- A. Propranolol
- B. Nadolol
- C. Carvedilol
- D. Timolol
Correct Answer: D
Rationale: Timolol, a beta-blocker, reduces aqueous humor production in glaucoma.
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Being competent in the use of information technology in clinical practice is expected in professional nurses. Advanced practice competence includes the ability to:
- A. Search for information using the most common search engines
- B. Serve as content experts in developing, implementing, and evaluating information systems
- C. Write programs to assure the integrity of health information
- D. Use information technology to prescribe drugs
Correct Answer: B
Rationale: Advanced practice nurses contribute expertise in IT system development and evaluation.
While collecting a medication history, the patient admits to doubling the recommended dosage of an over-the-counter (OTC) medication, saying It's harmless or they would require a prescription. What is the nurse's best response?
- A. OTC drugs are serious medications and carry serious risks if not taken as directed.
- B. Taking medications like that is careless and you could kill yourself doing it.
- C. Sometimes you need to take more than the package directs to treat the symptoms.
- D. Did you notify your doctor of the increased dosage you were taking?
Correct Answer: A
Rationale: OTC drugs are no less a medication than prescription drugs and carry the same types of risks for overdosage and toxicity if directions are not followed. Although increasing the dosage is careless and dangerous, it is important to use the information as a teaching opportunity rather than scolding the patient. Agreeing with the patient or asking her if she talked to the doctor misses the teaching opportunity, which could be harmful for the patient.
Drugs bound to albumin are inactive.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: True; drugs bound to albumin are inactive as only the free (unbound) fraction can interact with receptors or be metabolized/excreted.
A nurse working as a member of a research team is exploring the unique differences in drug response that each individual possesses based on his or her genetic makeup. This area of study is called:
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a person's unique genetic makeup. Pharmacotherapeutics is the branch of pharmacology that deals with the use of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes any costs involved in drug therapy.
If a 10 mg morphine produces a greater analgesic response than can achieved by ibuprofen at any dose, which of the following statements is correct?
- A. Morphine is less efficacious than is ibuprofen
- B. Morphine is less potent than is ibuprofen
- C. Morphine is a full agonist, and ibuprofen is a partial agonist
- D. Morphine is a better pain reliever than Ibuprofen
Correct Answer: D
Rationale: Morphine's greater maximal effect suggests higher efficacy, making it a better choice for pain relief, though potency isn't compared here.