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A nurse is caring for a client who is prescribed Isosorbide Mononitrate for chronic stable Angina and develops reflex tachycardia. Which of the following medications should the nurse expect to administer?
- A. Furosemide
- B. Captopril
- C. Ranolazine
- D. Metoprolol
Correct Answer: D
Rationale: Metoprolol , a beta-blocker, treats reflex tachycardia by slowing heart rate.
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A nurse working as a member of a research team is exploring the unique differences in drug response that each individual possesses based on his or her genetic makeup. This area of study is called:
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a person's unique genetic makeup. Pharmacotherapeutics is the branch of pharmacology that deals with the use of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes any costs involved in drug therapy.
A nurse is caring for a client who is admitted to undergo a surgical procedure. Which of the following preexisting conditions can be a contraindication for the use of Ketamine as an intravenous anesthetic?
- A. Peptic ulcer disease
- B. Breast cancer
- C. Diabetes mellitus
- D. Schizophrenia
Correct Answer: D
Rationale: Ketamine can exacerbate schizophrenia due to its psychomimetic effects.
A nursing student is reviewing information about the Controlled Substances Act of 1970. The student would expect to find which of the following as being regulated for drugs classified as controlled substances? Select one that does not apply
- A. Manufacturing
- B. Elimination
- C. Distribution
- D. Dispensing the drug
Correct Answer: B
Rationale: The Controlled Substances Act of 1970 regulates the manufacture, distribution, and dispensing of drugs classified as controlled substances. Elimination refers to the excretion of drugs from the body, a pharmacokinetic activity. The act does not address formulation of the drug.
The following drug causes a decrease in aqueous humour secretions from the ciliary body:
- A. Propranolol
- B. Nadolol
- C. Carvedilol
- D. Timolol
Correct Answer: D
Rationale: Timolol, a beta-blocker, reduces aqueous humor production in glaucoma.
James has hypothalamic-pituitary-adrenal axis suppression from chronic prednisone (a corticosteroid) use. He is at risk for what type of adverse drug reaction?
- A. Type B
- B. Type C
- C. Type E
- D. Type F
Correct Answer: B
Rationale: Chronic prednisone use causing HPA suppression is a Type C (chronic) ADR , linked to prolonged exposure, not idiosyncratic , withdrawal , or failure .