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Which mode of action has insulin in fatty cells?
- A. Decrease glycerol synthesis
- B. Increase synthesis of triglycerides
- C. Decrease fatty acid synthesis
Correct Answer: B
Rationale: Insulin promotes triglyceride synthesis in fat cells by enhancing glucose uptake and lipogenesis.
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A community health nurse visits a client at home. Prednisone 10 mg orally daily has been prescribed for the client and the nurse reinforces teaching for the client about the medication. Which statement, if made by the client, indicates that further teaching is necessary?
- A. I can take aspirin or my antihistamine if I need it.'
- B. I need to take the medication every day at the same time.'
- C. I need to avoid coffee, tea, cola, and chocolate in my diet.'
- D. If I gain more than 5 pounds a week, I will call my doctor.'
Correct Answer: A
Rationale: Aspirin and other over-the-counter medications should not be taken unless the client consults with the health care provider (HCP). The client needs to take the medication at the same time every day and should be instructed not to stop the medication. A slight weight gain as a result of an improved appetite is expected, but after the dosage is stabilized, a weight gain of 5 lb or more weekly should be reported to the HCP. Caffeine-containing foods and fluids need to be avoided because they may contribute to steroid-ulcer development.
A nurse is preparing to initiate IV therapy for an older adult client. Which of the following actions should the nurse plan to take?
- A. Use a disposable razor to remove excess hair on the extremity.
- B. Select the back of the client's hand to the catheter.
- C. Entered the veins by using a blood pressure cuff.
- D. Direct the client to raise his arm above his heart
Correct Answer: B
Rationale: The back of the hand is a common site for older adults due to accessible veins and reduced risk of complications.
Drugs do not metabolize the same way in all people. For what patient would a nurse expect to assess for an alteration in drug metabolism?
- A. A 35-year-old woman with cervical cancer
- B. A 41-year-old man with kidney stones
- C. A 50-year-old man with cirrhosis of the liver
- D. A 62-year-old woman in acute renal failure
Correct Answer: C
Rationale: The liver is the most important site of drug metabolism. If the liver is not functioning effectively, as in patients with cirrhosis, drugs will not metabolize normally so that toxic levels could develop unless dosage is reduced. A patient with cervical cancer or kidney stones would not be expected to have altered ability to metabolize drugs so long as no liver damage existed. The patient with renal failure would have altered excretion of the drugs through the renal system but metabolism would not be impacted.
Drugs bound to albumin are inactive.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: True; drugs bound to albumin are inactive as only the free (unbound) fraction can interact with receptors or be metabolized/excreted.
Amphetamine should not be taken with.....
- A. Paracetamol
- B. Aspirin
- C. MAO inhibitors
- D. Benzimidazole
Correct Answer: C
Rationale: Amphetamines combined with MAO inhibitors can cause a hypertensive crisis due to excessive catecholamine accumulation, a well-known dangerous interaction.