Nokea
The nurse is explaining how medications work to a group of peers and explains that disruption of a single step in any enzyme system disrupts what?
- A. Cell life
- B. Cell membrane
- C. Cell receptor sites
- D. Cell function
Correct Answer: D
Rationale: If a single step in one of the many enzyme systems is blocked, normal cell function is disrupted. Cell life and cell membrane may be impacted by disruption of some enzymes but not all enzymes. Receptor sites would not be disrupted by disruption in a single step in the enzyme system.
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Which of the following best describes the effect of propylthiouracil on thyroid hormone production?
- A. It blocks the release of thyrotropin-releasing hormone
- B. It inhibits uptake of iodide by thyroid cells
- C. It prevents the release of thyroid hormone from thyroglobulin
- D. It blocks iodination and coupling of tyrosines in thyroglobulin to form thyroid hormones
Correct Answer: D
Rationale: Propylthiouracil blocks iodination and coupling in thyroglobulin, inhibiting thyroid hormone synthesis.
First dose phenomenon is a characteristic side effect on initiation of antihypertensive therapy with
- A. Minoxidil
- B. Clonidine
- C. Metroprolol
- D. Prazosin
Correct Answer: B
Rationale: Clonidine can cause sedation or hypotension after the first dose.
Which of the following is a luminal amebecide drug?
- A. Metronidazole
- B. Emtine
- C. Doxycycline
- D. Dicloxinide
Correct Answer: D
Rationale: Diloxanide (likely misspelled as Dicloxinide) is a luminal amebicide used to eradicate cysts of Entamoeba histolytica in the intestinal lumen, unlike metronidazole, which targets systemic infection.
When moving to another state, what is the nurse responsible for becoming familiar with?
- A. Local policies and procedures for controlled substance administration
- B. Local providers Drug Enforcement Agency (DEA) number for prescribing controlled substances
- C. The agency monitoring controlled substances in the new state
- D. Board of Nursing regulations of controlled substances in the new state
Correct Answer: A
Rationale: The nurse needs to learn local policies and procedures for controlled substance administration because they can vary with some local governments more rigorous than others. Nurses do not memorize a providers DEA numbers. The DEA is a federal agency that monitors controlled substances in all states. State boards of nursing do not regulate controlled substances but may regulate how controlled substances are administered by nurses.
The direct costs of drug therapy include:
- A. The actual cost of acquiring the medication
- B. The loss of income due to illness
- C. Pain and suffering due to inadequate drug therapy
- D. The cost of a funeral associated with premature death
Correct Answer: A
Rationale: Direct costs are the tangible expenses of acquiring the drug itself.