The most frequent side effect of oral ampicillin is : *
- A. Nausea and vomiting
- B. Loose bowel movements
- C. Constipation
- D. Urticaria
Correct Answer: A
Rationale: The correct answer is A: Nausea and vomiting. Oral ampicillin commonly causes gastrointestinal side effects such as nausea and vomiting due to its impact on the gut flora. This side effect is a result of the antibiotic's mechanism of action and is well-documented in clinical practice. Choices B, C, and D are incorrect as loose bowel movements, constipation, and urticaria are not typically associated with oral ampicillin use.
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Which antibiotic is primarily bacteriostatic but becomes bactericidal at higher concentrations?:
- A. Erythromycin
- B. Tetracycline
- C. Chloramphenicol
- D. Ampicillin
Correct Answer: A
Rationale: Erythromycin is primarily bacteriostatic by inhibiting protein synthesis in bacteria. At higher concentrations, it can disrupt bacterial cell membranes, making it bactericidal. Tetracycline inhibits protein synthesis, Chloramphenicol blocks peptide bond formation, and Ampicillin disrupts bacterial cell wall synthesis. Therefore, A is correct because of its dual mechanism of action.
When the nurse is performing a genital examination on a male patient, the patient has an erection. The nurses most appropriate action or response is to:
- A. Ask the patient if he would like someone else to examine him.
- B. Continue with the examination as though nothing has happened
- C. reassure the patient that it is normal
- D. Stop the examination, leave the room while stating that the examination will resume at a later tim
Correct Answer: C
Rationale: The correct answer is C: reassure the patient that it is normal. An erection during a genital examination is a normal physiological response and not under the patient's control. By reassuring the patient, the nurse helps alleviate any potential embarrassment or anxiety. Asking for someone else (A) may further embarrass the patient. Continuing as if nothing happened (B) may ignore the patient's emotional well-being. Stopping the examination and leaving (D) without explanation can create confusion and discomfort.
Which is not a relatively common finding in ESRF patients?
- A. Metastatic calcification.
- B. Peripheral neuropathy
- C. Hypophosphatemia
- D. Hyperparathyroidism
Correct Answer: C
Rationale: The correct answer is C: Hypophosphatemia. In end-stage renal failure (ESRF) patients, hypophosphatemia is not a common finding due to impaired renal excretion of phosphate. Metastatic calcification (A) occurs due to high calcium-phosphate product, peripheral neuropathy (B) can result from uremic toxins, and hyperparathyroidism (D) is common in ESRF due to secondary hyperparathyroidism. Therefore, hypophosphatemia is the least likely finding in ESRF patients.
A physician is caring for a patient with a urinary tract infection. The physician would expect the plan of care to include:
- A. Antibiotics and phenazopyridine.
- B. Erythropoietin and stent placement.
- C. Hormonal therapy and intravenous fluids.
- D. Hourly urine output measurements and antibiotics.
Correct Answer: A
Rationale: The correct answer is A: Antibiotics and phenazopyridine. Antibiotics are essential to treat the bacterial infection causing the UTI. Phenazopyridine can help relieve urinary discomfort. Erythropoietin and stent placement (B) are not indicated for UTI. Hormonal therapy and IV fluids (C) are not standard treatments for UTI. Hourly urine output measurements and antibiotics (D) are not typically necessary, as antibiotics alone are sufficient for treating UTIs.
A patient with HIV-AIDS being treated with combined antiviral drugs and immunosuppressive agents, develops an opportunistic infection caused by Pneumocystis carinii. Which of the following drugs most likely be used in the treatment of pulmonary infection caused by P. carinii?
- A. Metronidazole
- B. Carbenicillin
- C. Trimethoprim/Sulfamethoxazole
- D. Penicillin G
Correct Answer: C
Rationale: The correct answer is C: Trimethoprim/Sulfamethoxazole. This combination is the first-line treatment for Pneumocystis carinii pneumonia in patients with HIV-AIDS due to its efficacy against the organism. Trimethoprim inhibits dihydrofolate reductase, while sulfamethoxazole inhibits dihydropteroate synthase, both essential enzymes for folate synthesis in bacteria and protozoa like P. carinii. Metronidazole (A) is used for anaerobic infections, Carbenicillin (B) is a penicillinase-resistant penicillin used for Gram-negative infections, and Penicillin G (D) is a narrow-spectrum antibiotic mainly used for Gram-positive infections.