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What is the medical term for a blood clot that forms within a blood vessel?
- A. Thrombosis
- B. Embolus
- C. Hemorrhage
- D. Hemostasis
Correct Answer: A
Rationale: The correct answer is A: Thrombosis. Thrombosis refers to the formation of a blood clot within a blood vessel. The process involves the coagulation of blood components to form a clot. This can lead to blockages in blood vessels, potentially causing serious health issues like stroke or heart attack.
Choice B: Embolus refers to a blood clot that has traveled from its original site and lodged in a different blood vessel. Choice C: Hemorrhage is the medical term for bleeding. Choice D: Hemostasis refers to the body's process of stopping bleeding, not the formation of a blood clot.
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The nurse is reinforcing teaching to a person who has tested positive for HIV. Which test should the nurse explain is done to confirm the diagnosis of HIV?
- A. Western blot
- B. Rheumatoid factor
- C. Antinuclear antibodies
- D. Immunoglobulin assay
Correct Answer: A
Rationale: The correct answer is A: Western blot. This test is used to confirm the diagnosis of HIV by detecting specific antibodies produced in response to the virus. It is considered the gold standard for confirming HIV infection due to its high specificity and sensitivity. The other choices (B, C, D) are not used to diagnose HIV. Rheumatoid factor and antinuclear antibodies are tests for autoimmune conditions, while immunoglobulin assay measures levels of antibodies in the blood, not specific to HIV.
All of the following are true EXCEPT
- A. An epitope is a small portion of a macromolecule
- B. the variable region domains contain the antigen recognition site
- C. an antigenic determinant is a paratope
- D. The class of an immunoglobulin is determined by its heavy chain
Correct Answer: C
Rationale: The correct answer is C because an antigenic determinant is not a paratope, but an epitope. Epitope is a small portion of a macromolecule that is recognized by antibodies. Variable region domains of antibodies contain the antigen recognition site. The class of an immunoglobulin is indeed determined by its heavy chain. Therefore, C is the only statement that is not true.
Why do opportunistic diseases develop in an individual with AIDS?
- A. They are side effects of drug treatment of AIDS.
- B. They are sexually transmitted to individuals during exposure to HIV.
- C. They are characteristic in individuals with stimulated B and T lymphocytes.
- D. These infections or tumors occur in a person with an incompetent immune system.
Correct Answer: D
Rationale: Opportunistic diseases arise because the immune system is severely compromised in individuals with AIDS, making them susceptible to infections and cancers they would otherwise resist.
When teaching the patient with cancer about chemotherapy, which approach should the nurse take?
- A. Avoid telling the patient about possible side effects of the drugs to prevent anticipatory anxiety
- B. Explain that antiemetics,antidiarrheals and analgesics will be provided as needed to control side effects
- C. Assure the patient that the side effects from chemotherapy are uncomfortable but never life threatening
- D. Inform the patient that chemotherapy-related alopecia is usually permanent but can be managed with lifelong use of wigs
Correct Answer: B
Rationale: Providing information about available supportive therapies helps patients manage side effects effectively.
Select incorrect mechanism for the development of autoimmune disorder.
- A. A second exposure to an allergen.
- B. Cross-reaction of antibodies formed against foreign antigens with self-antigens.
- C. Exposure of previously 'hidden' self-antigens to the adaptive immune system.
- D. Mutation followed by the appearance of membrane proteins not previously present.
Correct Answer: A
Rationale: The correct answer is A. A second exposure to an allergen does not lead to the development of autoimmune disorders. The key mechanisms involved in autoimmune disorders are self-tolerance breakdown and immune system attacking self-antigens.
Explanation:
1. B: Cross-reaction of antibodies formed against foreign antigens with self-antigens is a possible mechanism for autoimmune disorders.
2. C: Exposure of previously 'hidden' self-antigens to the adaptive immune system can trigger autoimmune responses.
3. D: Mutation followed by the appearance of membrane proteins not previously present can lead to autoimmune disorders, as the immune system may recognize these proteins as foreign.
Summary:
Choice A is incorrect because a second exposure to an allergen does not cause the immune system to target self-antigens, which is the hallmark of autoimmune disorders. Choices B, C, and D are more plausible mechanisms for the development of autoimmune disorders.