Nursing Drug Classification System

Which one of the following is a fundamental difference between competitive and noncompetitive antagonist?

A. Competitive and non competitive work on different receptors

B. Competitive antagonist reduces agonist potency (increase EC50) and non competitive antagonist reduces agonist efficacy (decrease E max)

C. There is no difference between them, they are exactly the same

D. Non competitive antagonist causes an upward shift of the E max while competitive antagonist does the opposite

Test Board