Multiple Choice Questions on Respiratory System Related

Review Multiple Choice Questions on Respiratory System related questions and content

2,3 DPG causes shifting of Oxygen dissociation curve in Adult Hb to Right because

  • A. It increases Oxygen affinity for Hemoglobin
  • B. It binds to Beta chain of Hb
  • C. Its concentration is high in adults
  • D. It lacks Hb binding sites
Correct Answer: B

Rationale: The correct answer is B because 2,3 DPG binds to the Beta chain of Hemoglobin, reducing its oxygen affinity, causing a right shift in the Oxygen dissociation curve. This change allows for easier oxygen unloading in tissues. Choice A is incorrect as 2,3 DPG decreases, not increases, oxygen affinity. Choice C is irrelevant as its concentration is not a factor in the shifting of the curve. Choice D is incorrect as 2,3 DPG does bind to Hemoglobin, specifically to the Beta chain.