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45 year old female has a diabetes mellitus. Endocrinologist prescribes treatment, which has a side effect as hypoglycemia and weight gain. Which of the following drug is prescribed?
- A. Canagliflozin
- B. Exenatide
- C. Gliburide
- D. Pramlintide
Correct Answer: C
Rationale: Gliburide, a sulfonylurea, commonly causes hypoglycemia and weight gain due to increased insulin release.
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In an acute attack of migraine, the drug of choice is
- A. Ergotamine tartrate
- B. Methysergide
- C. Propranolol
- D. Caffeine
Correct Answer: A
Rationale: Ergotamine tartrate is the drug of choice for acute migraine.
The nurse is assessing a diabetic patient who has presented at the clinic reporting several hypoglycemic episodes during the past 3 weeks. The nurse questions the patient about the use of herbal or alternative therapies, suspecting what herbal remedy could cause the hypoglycemic episodes?
- A. St. John's wort
- B. Kava
- C. Fish oil
- D. Ginseng
Correct Answer: D
Rationale: Ginseng is known to decrease blood sugar levels. If the patient used this in combination with his or her oral antidiabetic agent, diet, and exercise, his or her blood sugar could drop below therapeutic levels. St. John's wort interacts with many drugs, but not with antidiabetic agents. Kava is associated with liver toxicity. Fish oil has been associated with decreased coronary artery disease.
What is a prodrug
- A. Drag which increases efficiency of another drug
- B. Metabolic end product
- C. Inactive drag which gets activated in the body
- D. Drag which competes with another for metabolism
Correct Answer: C
Rationale: A prodrug is inactive until metabolized into an active form in the body.
The Vaccine Adverse Events Reporting System is:
- A. A mandatory reporting system for all health-care providers when they encounter an adverse vaccine event
- B. A voluntary reporting system that health-care providers or consumers may use to report vaccine adverse events
- C. Utilized to send out safety alerts regarding emerging vaccine safety issues
- D. Activated when a vaccine has been proven to cause significant adverse effects
Correct Answer: B
Rationale: VAERS is a voluntary system for reporting vaccine ADRs by providers or consumers, not mandatory or alert-only .
All of the following adverse effects commonly occur in glucocorticoid therapy except:
- A. Osteoporosis
- B. Increased risk of infection
- C. Hypotension
- D. Emotional disturbances
Correct Answer: C
Rationale: Glucocorticoids cause hypertension, not hypotension, due to mineralocorticoid effects and fluid retention.