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A 60 year old male patient with a history of postural hypotension has just been diagnosed with benign prostatic hyperplasia. Which ONE of the following drugs is most suitable for the management of his condition?
- A. Prazosin
- B. Terazosin
- C. Doxazosin
- D. Tamsulosin
Correct Answer: D
Rationale: Tamsulosin, a selective alpha-1A blocker, minimizes postural hypotension compared to non-selective options.
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Drug of choice in phenothiazine induced parkinsonism is
- A. Levodopa
- B. Haloperidol
- C. Metoclopramide
- D. None of the above
Correct Answer: A
Rationale: Levodopa counters phenothiazine-induced parkinsonism.
If 10 mg of naproxen produces the same analgesic response as 100 mg of ibuprofen, which of the following statements is correct?
- A. Naproxen is more efficacious than is ibuprofen
- B. Naproxen is more potent than ibuprofen
- C. Naproxen is full agonist, and ibuprofen is a partial agonist
- D. Naproxen is a competitive antagonist
Correct Answer: B
Rationale: Lower dose for the same effect indicates naproxen is more potent (lower EC50) than ibuprofen.
Live attenuated influenza vaccine (FluMist) may be administered to:
- A. All patients over 6 months of age
- B. Patients between ages 2 and 49 with no risk factors
- C. Patients with an upper respiratory infection (URI) or asthma
- D. Pregnant women
Correct Answer: B
Rationale: FluMist is approved for healthy individuals aged 2-49; URI/asthma or pregnancy are contraindications.
The nurse explains that what drug resource book is compiled from package inserts?
- A. Nurses Drug Guide
- B. Physicians Desk Reference (PDR)
- C. Drug Facts and Comparisons
- D. AMA Drug Evaluations
Correct Answer: B
Rationale: The PDR is a compilation of information found on package inserts. The Nurses Drug Guide uses more easily understood language and incorporates nursing considerations and patient teaching points. Drug Facts and Comparisons includes cost comparison, often not found in other drug resource guides. The AMA Drug Evaluations is far less biased than the PDR and includes drugs still in the research stage of development.
All nonsteroidal anti-inflammatory drugs (NSAIDS) have an FDA Black Box Warning regarding:
- A. Potential for causing life-threatening GI bleeds
- B. Increased risk of developing systemic arthritis with prolonged use
- C. Risk of life-threatening rashes, including Stevens-Johnson
- D. Potential for transient changes in serum glucose
Correct Answer: A
Rationale: NSAIDs carry a Black Box Warning for GI bleeding risk; rashes or glucose aren't highlighted.