Nokea
A 64-year-old woman with a history of type 2 diabetes is diagnosed with heart failure. Which of the following medications would be a poor choice for controlling her diabetes?
- A. Exenatide
- B. Glyburide
- C. Nateglinide
- D. Rosiglitazone
Correct Answer: D
Rationale: Rosiglitazone can worsen heart failure due to fluid retention and edema.
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Monitoring for a child on methylphenidate for attention deficit hyperactivity disorder (ADHD) includes:
- A. ADHD symptoms
- B. Routine height and weight checks
- C. Amount of methylphenidate being used
- D. All of the above
Correct Answer: D
Rationale: All are monitored: symptom control, growth effects, and medication use.
A nurse is caring for a client who has a new prescription for Phenelzine for the treatment of depression. Which of the following indicates that the client has developed an adverse effect of this medication?
- A. Orthostatic hypotension
- B. Hearing loss
- C. Gastrointestinal bleeding
- D. Weight loss
Correct Answer: A
Rationale: Phenelzine, an MAOI, commonly causes orthostatic hypotension due to its effect on blood pressure regulation.
All are explained on pharmacogenetic conditions except
- A. G6PD deficiency
- B. Warfarin insensitivity
- C. Adenosine deaminase deficiency
- D. Malignant hyperthermia
Correct Answer: C
Rationale: Adenosine deaminase deficiency is not typically pharmacogenetic; others are.
All of following are examples of prodrugs except
- A. Levodopa
- B. Enlapril
- C. Omeprazole
- D. Indomethacin
Correct Answer: D
Rationale: Prodrugs (e.g., levodopa, enalapril, omeprazole) are inactive until metabolized. Indomethacin is active as administered.
Dulcea has type 2 diabetes and a high triglyceride level. She has gemfibrozil prescribed to treat her hypertriglyceridemia. A history of which of the following might contraindicate the use of this drug?
- A. Reactive airway disease/asthma
- B. Inflammatory bowel disease
- C. Allergy to aspirin
- D. Gallbladder disease
Correct Answer: D
Rationale: Gemfibrozil increases gallstone risk, contraindicating its use in gallbladder disease.