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A 75 year old male with BPH has continues to have urinary symptoms of * prostatic obstruction after trial of alpha blocking drug tamsulosin . Dutasteride is added to his therapy,he is also taking hydrochlorothiazide sildenafil and
- A. Which of the following medication could have an interaction with dutasteride?
- B. Tamsulosin
- C. Testosterone
- D. Seldinal
Correct Answer: D
Rationale: The correct answer is D: Sildenafil. Dutasteride and sildenafil are both metabolized by the same enzymes in the liver, specifically CYP3A4 and CYP2C9. When taken together, sildenafil can increase the blood levels of dutasteride, leading to a higher risk of side effects. Tamsulosin (choice B) is commonly used in combination with dutasteride for BPH without significant interactions. Testosterone (choice C) is not typically used in BPH treatment and does not interact significantly with dutasteride. Therefore, the potential interaction between dutasteride and sildenafil is the reason why choice D is correct.
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A 22-year-old woman has been considering using oral contraceptives. As a part of her health history, the nurse should ask:
- A. Do you have a history of heart murmurs?
- B. Will you be in a monogamous relationship?
- C. Have you carefully thought this choice through?
- D. If you smoke, how many cigarettes do you smoke per day?
Correct Answer: D
Rationale: The correct answer is D because smoking increases the risk of cardiovascular complications with oral contraceptives. By asking about the number of cigarettes smoked per day, the nurse can assess the level of risk. Choice A is incorrect as it is not directly related to the safety of oral contraceptives. Choice B is important for overall sexual health but not directly related to the safety of oral contraceptives. Choice C is vague and does not provide specific information about potential risks associated with oral contraceptives.
Which test is required for a diagnosis of pyelonephritis?
- A. Renal biopsy
- B. Blood culture
- C. Intravenous pyelogram (IVP)
- D. Urine for culture and sensitivity
Correct Answer: D
Rationale: The correct answer is D, Urine for culture and sensitivity. This test is required for a diagnosis of pyelonephritis as it helps identify the specific bacteria causing the infection and determines the most effective antibiotic treatment. Renal biopsy (A) is not typically required for diagnosing pyelonephritis. Blood culture (B) may be helpful in severe cases but is not specific for pyelonephritis. Intravenous pyelogram (IVP) (C) is a radiological test used to visualize the urinary tract but does not confirm the diagnosis of pyelonephritis.
If necessary, your physician can increase your dose up to 40 mg per day.
- A. TRUE
- B. FALSE
- C. Maybe
- D. Not mentioned
Correct Answer: A
Rationale: Step 1: The statement indicates the possibility of increasing the dose up to 40 mg, implying that it is within the physician's discretion.
Step 2: The use of the word "can" suggests the potential for the physician to make such an adjustment.
Step 3: The phrase "if necessary" implies that the dose adjustment will be based on the individual's specific needs.
Step 4: Therefore, it is true that the physician has the authority to increase the dose up to 40 mg per day based on the patient's condition and requirements.
The best time for a woman of childbearing age to perform breast self-examination is
- A. during her menstrual period
- B. 2 days before the onset of her menstrual period
- C. 1 week after her menstrual period ends
- D. the day her menstrual period begins
Correct Answer: C
Rationale: The best time for a woman of childbearing age to perform breast self-examination is 1 week after her menstrual period ends. This is because breast tissue tends to be less tender and lumpy during this time, making it easier to detect any abnormalities. Performing the examination at this time allows for a more accurate assessment of the breasts. Additionally, hormonal changes during the menstrual cycle can affect breast tissue, so performing the examination post-menstruation reduces the likelihood of false alarms. Choices A, B, and D are not ideal times as breast tenderness and hormonal fluctuations during the menstrual period can make it challenging to accurately detect abnormalities.
Combivir is a combination therapy used to treat HIV and AIDS include which * of the following drugs?
- A. Lamivudine and stavudine
- B. Lamivudine and zidovudine
- C. Abacavir and zidovudine
- D. Abacavir and stavudine
Correct Answer: B
Rationale: The correct answer is B: Lamivudine and zidovudine. Combivir is a combination therapy that consists of these two drugs. Lamivudine and zidovudine work together to inhibit the replication of the HIV virus. Lamivudine is a nucleoside reverse transcriptase inhibitor, while zidovudine is a nucleoside analog reverse transcriptase inhibitor. Both drugs target different stages of the HIV life cycle, making them effective when used in combination.
Choice A (Lamivudine and stavudine) is incorrect because stavudine is not part of the Combivir combination therapy. Choice C (Abacavir and zidovudine) is incorrect because abacavir is not included in Combivir. Choice D (Abacavir and stavudine) is incorrect because stavudine is not part of the Combivir combination therapy.