A baby is born with a penis, a scrotum with no testes, no vagina, and XX chromosomes. This condition is referred to as hermaphroditism. Which of the following could cause this abnormality?
Correct Answer: D
Rationale: The correct answer is D: Abnormally high levels of testosterone in the maternal blood. This can cause virilization of the female fetus, leading to the development of male external genitalia. Testosterone exposure during fetal development can result in the formation of a penis and scrotum without testes in a genetic female (XX).
Rationale:
1. Testosterone is responsible for the development of male external genitalia.
2. XX chromosomes indicate a genetic female.
3. Lack of testes indicates incomplete masculinization.
4. High levels of testosterone can override the default female development pattern.
Other choices are incorrect because:
A: Human chorionic gonadotropin does not directly affect fetal genital development.
B: Estrogen is not responsible for male genital development.
C: Luteinizing hormone does not directly influence the development of external genitalia in the fetus.