Nokea
A client is being treated for tuberculosis. Which medications are used to treat this condition?(Select one that does not apply.)
- A. Streptomycin sulfate
- B. rifabutin
- C. Ethambutol (Myambutol)
- D. Gentamicin (Garamycin)
Correct Answer: D
Rationale: TB treatment uses streptomycin, ethambutol, rifabutin, ethionamide, and pyrazinamide; amoxicillin and gentamicin are not standard. Streptomycin sulfate, ethambutol, rifabutin, ethionamide, and pyrazinamide are used to treat tuberculosis.
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Ultra-rapid metabolizers of drugs may have:
- A. To have dosages of drugs adjusted downward to prevent drug accumulation
- B. Active drug rapidly metabolized into inactive metabolites, leading to potential therapeutic failure
- C. Increased elimination of active, nonmetabolized drug
- D. Slowed metabolism of a prodrug into an active drug, leading to an accumulation of prodrug
Correct Answer: B
Rationale: Ultra-rapid metabolizers (e.g., CYP2D6) quickly inactivate drugs , risking therapeutic failure, requiring higher doses, not lower or slowed metabolism .
The following are recognized effects of propranolol except
- A. Increases microcoronary blood flow
- B. Decrease in heart rate
- C. Decrease in cardiac output
- D. Reduction in ventricular systolic pressure
Correct Answer: A
Rationale: Propranolol reduces coronary flow; other effects are correct.
Avoid concurrent administration of exenatide with which of the following drugs?
- A. Digoxin
- B. Warfarin
- C. Lovastatin
- D. All of the above
Correct Answer: D
Rationale: Exenatide delays gastric emptying, potentially affecting absorption of digoxin , warfarin , and lovastatin .
Which of the following can be used for treatment of hypothyroidism:
- A. Liothironine
- B. Iodides (lugol solution)
- C. Carbimazole
- D. Methimazole
Correct Answer: A
Rationale: Liothyronine (T3) is used to replace thyroid hormone in hypothyroidism.
A nurse is teaching a client who has a new prescription for Verapamil to control Hypertension. Which of the following instructions should the nurse include?
- A. Increase the amount of dietary fiber in the diet.
- B. Drink grapefruit juice daily to increase vitamin C intake.
- C. Decrease the amount of calcium in the diet.
- D. Withhold food for 1 hr after the medication is taken
Correct Answer: A
Rationale: Fiber prevents constipation, a common side effect of verapamil; grapefruit juice interacts adversely.