A group of nursing students are reviewing information about antiviral agents. The students demonstrate understanding of the information when they identify which of the following as a drug category used for treating viral infections? Select all that apply.
- A. Antiattachment
- B. Antiretroviral
- C. Antitranscription
- D. Antireplication
- E. Antiviral
Correct Answer: B,E
Rationale: The drugs used to treat viral infections can be split into two categories: antiviral and antiretroviral agents.
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After teaching a group of nursing students about antiretroviral drugs, the instructor determines that the teaching was successful when the students identify that these drugs are used to treat which infections? Select all that apply.
- A. Hepatitis C virus (HCV)
- B. Human immunodeficiency virus (HIV)
- C. Acquired immunodeficiency syndrome (AIDS)
- D. Herpes simplex virus (HSV) 1
- E. Herpes simplex virus (HSV) 2
Correct Answer: B,C
Rationale: Antiretroviral drugs are used to treat HIV and AIDS.
When teaching a client about antiviral therapy, the nurse would include information about the possibility of which adverse reactions? Select all that apply.
- A. Rash
- B. Sedation
- C. Chills
- D. Diarrhea
- E. Headache
Correct Answer: A,D,E
Rationale: Adverse reactions associated with antiviral drugs include nausea, vomiting, diarrhea, headache, rash, fever, and insomnia.
A client is ordered to receive an antiretroviral agent that is categorized as a nonnucleoside reverse transcriptase inhibitor. Which of the following would the nurse expect to administer?
- A. Indinavir
- B. Nevirapine
- C. Saquinavir
- D. Ritonavir
- E. Zidovudine
Correct Answer: B
Rationale: Nevirapine is classified as a nonnucleoside reverse transcriptase inhibitor. Indinavir, saquinavir, and ritonavir are classified as protease inhibitors. Zidovudine is a nucleoside reverse transcriptase inhibitor.
A patient is being treated with saquinavir. The nurse would assess the patient for which of the following?
- A. Increase in patient's weight
- B. Evidence of liver dysfunction
- C. Photosensitivity
- D. Allergic skin reaction
- E. Diarrhea
Correct Answer: A
Rationale: Patients taking saquinavir experience redistribution of body fat, with the movement to the center of the body. The nurse should spend time with these patients, encouraging them to verbalize their feelings regarding this change in appearance. Taking saquinavir does not cause liver dysfunction, photosensitivity, allergic skin reactions, or diarrhea.
A nurse is preparing to administer ribavirin via inhalation to a client. Which of the following would the nurse need to keep in mind? Select all that apply.
- A. Administration is via a nebulizer.
- B. Solution should be discarded and replaced every 24 hours.
- C. Respiratory status can be worsened by the drug.
- D. Extrapyramidal effects can occur upon administration of the drug.
- E. Women of childbearing age should not inhale the drug.
Correct Answer: B,C,E
Rationale: Ribavirin is administered by inhalation using a small-particle aerosol generator. The solution should be discarded and replaced every 24 hours. This drug can worsen respiratory status, this drug is pregnancy category \mathrm{X}, and women of childbearing age should take care not to inhale the drug.
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