A nurse in a clinic is caring for a group of clients. The nurse should contact the provider about a potential contraindication to a medication for which of the following clients?
- A. A client at 8 weeks of gestation who asks for an influenza immunization
- B. A client who takes Prednisolone and has a no fungal infection
- C. A client who has chronic liver disease and is taking hydrocortone
- D. A client who has Peptic Ulcer Disease, takes Sucralfate, and tells the nurse she has started taking OTC Aluminum Hydroxide
Correct Answer: C
Rationale: Prednisolone worsens fungal infections, hydrocortisone is risky in liver disease, and warfarin with pregnancy increases bleeding risk.
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The therapeutic goals when prescribing include(s):
- A. Curative
- B. Palliative
- C. Preventive
- D. All of the above
Correct Answer: D
Rationale: Therapeutic goals can be curative, palliative, or preventive , depending on the patient's condition and needs.
After teaching a group of nursing students about pharmacokinetics, the instructor determines that the teaching was successful when the students identify which of the following as a phase? (Select one that does not apply.)
- A. Absorption
- B. Distribution
- C. Administration
- D. Metabolism
Correct Answer: C
Rationale: The pharmacokinetic phases are absorption, distribution, metabolism, and excretion. The acronym ADME is a helpful way to remember the pharmacokinetic phases.
John has clonidine, a centrally acting adrenergic blocker, prescribed for his hypertension. He should:
- A. Not miss a dose or stop taking the drug because of potential rebound hypertension
- B. Increase fiber in the diet to treat any diarrhea that may occur
- C. Reduce fluid intake to less than 2 liters per day to prevent fluid retention
- D. Avoid sitting for long periods, as this can lead to deep vein thrombosis
Correct Answer: A
Rationale: Clonidine withdrawal can cause rebound hypertension, making adherence critical.
Methanol causes blindness due to its
- A. Hypersensitivity reactions
- B. Conjugated products
- C. Idiosyncratic reaction
- D. Oxidative products
Correct Answer: D
Rationale: Methanol's metabolite, formic acid (oxidative product), damages the optic nerve, causing blindness.
Ototoxicity is more likely if aminoglycosides are administered with which of the following drug classes?
- A. Loop diuretics
- B. Metformin
- C. Vancomycin
- D. Cephalosporins
Correct Answer: A
Rationale: Loop diuretics (e.g., furosemide) enhance aminoglycoside ototoxicity by increasing inner ear damage risk.
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